Evidence map›Paper›PMID 31583248›Full record

SynthesisJournal of diabetes research2019

The Association between Helicobacter pylori Infection and Glycated Hemoglobin A in Diabetes: A Meta-Analysis.

Jinhu Chen, Yuling Xing, Liying Zhao, Huijuan Ma

Open access · goldAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Journal of diabetes research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. A Significant Association between Type 1 Diabetes andMedicina (Kaunas, Lithuania) · 2024
    Pooled it
  2. Article
  3. The Prevalence ofMedicina (Kaunas, Lithuania) · 2025
    Article
  4. Article
  5. Systemic Impact ofJGH open : an open access journal of gastroenterology and hepatology · 2025
    Article
  6. Association betweenFrontiers in nutrition · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Frontiers in nutrition · 2023
    Article
  11. Review
  12. Article
  13. Children (Basel, Switzerland) · 2022
    Review
  14. Extra-Gastroduodenal Manifestation andArchives of Razi Institute · 2022
    Article
  15. Frontiers in immunology · 2022
    Review
  16. Review
  17. Gut Microbiota: The Missing Link BetweenFrontiers in endocrinology · 2021
    Review
  18. World journal of gastroenterology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jinhu ChenDepartment of Endocrinology, Hebei General Hospital, Shijiazhuang 050017, China.ORCID https://orcid.org/0000-0002-4923-5076
Yuling XingGraduate School of Hebei Medical University, Shijiazhuang 050017, China.ORCID https://orcid.org/0000-0001-6024-9439
Liying ZhaoGraduate School of Hebei Medical University, Shijiazhuang 050017, China.
Huijuan MaDepartment of Endocrinology, Hebei General Hospital, Shijiazhuang 050017, China.ORCID https://orcid.org/0000-0003-3711-7942
Hebei Medical University · CNHebei General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe association between Helicobacter pylori infection and glycated hemoglobin A has been confirmed in many studies, but these conclusions are still contradictory and controversial. Therefore, we conducted a meta-analysis to resolve the problem of inconsistent results in diabetes.

methodsA comprehensive search was conducted on related researches published in PubMed, Embase, and China Academic Journal Full-text Database (CNKI) from the inception of each database to April 2019. Fixed or random effects model was used to pool the weighted mean difference with 95% confidence interval from individual studies. Subgroup and sensitivity analyses were also performed. Publication bias was estimated by funnel plot, Egger's test, and fail-safe numbers.

results35 studies with 4,401 participants with diabetes were included in the meta-analysis. Glycated hemoglobin A levels were elevated in patients with Helicobacter pylori infection compared with patients without Helicobacter pylori infection (WMD = 0.50, 95% CI: 0.28-0.72,

conclusionThe meta-analysis might indicate a correlation between Helicobacter pylori infection and glycated hemoglobin A levels in diabetes.

Indexed as

Helicobacter pyloriDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2Glycated HemoglobinHelicobacter InfectionsHumansGlycated Hemoglobin

Identifiers

PMID31583248
PMCPMC6754895
OpenAlexW2971938873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.