Evidence map›Paper›PMID 31583232›Full record

ArticleJournal of advanced veterinary and animal research2019

Selenium-enriched probiotics improve hepatic protection by regulating pro-inflammatory cytokines and antioxidant capacity in broilers under heat stress conditions.

Alam Zeb Khan, Imdad Ullah Khan, Shakirullah Khan, Samreen Afzal, Mohammad Hamid, Muhammad Tariq, Ikram Ul Haq, Naimat Ullah, Mumtaz Ali Khan, Shahid Bilal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Alam Zeb KhanFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Imdad Ullah KhanFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Shakirullah KhanFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Samreen AfzalCollege of Life Sciences, Nanjing Agricultural University, Nanjing, China.
Mohammad HamidInstitute of Nutritional and Metabolic Disorders of Domestic Animals and Fowls, Nanjing Agricultural University, Nanjing, China.
Muhammad TariqFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Ikram Ul HaqFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Naimat UllahFaculty of Veterinary and Animal Sciences, Gomal University, Dera Ismail Khan, Pakistan.
Mumtaz Ali KhanUniversity of Veterinary and Animal Sciences, Lahore, Pakistan.
Shahid BilalCollege of Life Sciences, Nanjing Agricultural University, Nanjing, China.
Kehe HuwangCollege of Life Sciences, Nanjing Agricultural University, Nanjing, China.
Ran LiuKey Laboratory of Environmental Medicine Engineering Ministry of Education, School of Public Health, Southeast University, Nanjing, China.
Gomal University · PKNanjing Agricultural University · CNSoutheast University · CNUniversity of Veterinary and Animal Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveHigh ambient temperature in poultry is a challenging and fatal stress among environmental factors. It affects the production quality, damages the liver, and increases mortality in broilers. The present study is focused to explore appropriate utilization of Selenium (Se) as a feed additive in broiler chickens against high temperature. MATERIALS AND

methodsDay-old male broiler chickens (Ross 308) (

resultsHepatic analyses revealed the decreased level of malondialdehyde, whereas glutathione, glutathione peroxidase (GSH-Px), and superoxide dismutase levels were increased in the SP group. Furthermore, supplementation of SP significantly up-regulated the mRNA expression of glutathione peroxidase 1 (GPx1), GPx4, IL6, and IL10 and down-regulated the expression of pro-inflammatory cytokines.

conclusionIt is thus concluded that SP as a potential nutritive supplement may facilitate hepatic protection by suppressing hepatic oxidation, inflammation, and necrosis during the high ambient temperature of summer.

Indexed as

broilerheat stressinflammationliverpro-inflammatory cytokinesSelenium-enriched probiotics

Identifiers

PMID31583232
PMCPMC6760513
OpenAlexW2972033973

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.