Evidence map›Paper›PMID 31583227›Full record

ArticleJournal of advanced veterinary and animal research2019

Molecular characterization of MHC II DRB3 gene of swamp- and riverine-type water buffaloes.

Noraine P Medina, Arren Christian M De Guia, Virginia M Venturina, Claro N Mingala

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced veterinary and animal research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 89% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Noraine P MedinaCollege of Veterinary Science and Medicine, Central Luzon State University, Science City of Munoz, Nueva Ecija, The Philippines.
Arren Christian M De GuiaCollege of Veterinary Science and Medicine, Central Luzon State University, Science City of Munoz, Nueva Ecija, The Philippines.
Virginia M VenturinaCollege of Veterinary Science and Medicine, Central Luzon State University, Science City of Munoz, Nueva Ecija, The Philippines.
Claro N MingalaCollege of Veterinary Science and Medicine, Central Luzon State University, Science City of Munoz, Nueva Ecija, The Philippines.
Central Luzon State University · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMajor histocompatibility complex (MHC) is a set of molecular proteins on the surface of antigen presenting cells encoded by a large gene family which are important parts of the immune system. This study was conducted to convey information on the genetic characteristics of the MHC II DRB3 gene in riverine and swamp buffaloes. MATERIALS AND

methodsCharacterization of MHC II DRB3 gene was carried out using polymerase chain reaction (PCR)-based assay. Thirty-milliliter milk samples were collected from 10 swamp-type and 10 riverine-type buffaloes. RNA from milk samples were extracted using Trizol and then followed by reverse transcription-PCR (RT-PCR).

resultsThe phylogenetic analysis with 1,000 bootstrap replications clearly showed complex parsimony in MHC II DRB3 gene between 10 riverine- and 10 swamp-type but also confirmed that the samples are similar to

conclusionBased on the molecular data, the current study conforms to other works of literature that this gene is highly polymorphic which can be due to its function in the immune responsiveness and disease resistance. Further study on the immunological response of MHC II DRB3 to infection may elucidate its underlying function and role in the protection against specific disease of animals.

Indexed as

MHC II DRB3phylogenetic analysiswater buffaloes

Identifiers

PMID31583227
PMCPMC6760514
OpenAlexW2971749200

What OpenQuestion holds

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.