Evidence map›Paper›PMID 31583070›Full record

ArticleEvoDevo2019

Genomic analysis of the tryptome reveals molecular mechanisms of gland cell evolution.

Leslie S Babonis, Joseph F Ryan, Camille Enjolras, Mark Q Martindale

Open access · goldAbstract read
In one paragraph

Article in EvoDevo, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

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  10. A novel regulatory gene promotes novel cell fate by suppressing ancestral fate in the sea anemoneProceedings of the National Academy of Sciences of the United States of America · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Leslie S Babonis1Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, FL 32080 USA.ORCID 0000-0002-9783-4882
Joseph F Ryan1Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, FL 32080 USA.
Camille Enjolras1Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, FL 32080 USA.
Mark Q Martindale1Whitney Laboratory for Marine Bioscience, University of Florida, St. Augustine, FL 32080 USA.
Whitney Museum of American Art · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding the drivers of morphological diversity is a persistent challenge in evolutionary biology. Here, we investigate functional diversification of secretory cells in the sea anemone

resultsWe demonstrate regionalized expression of gland cell subtypes in the internal ectoderm of

conclusionsTogether, these results reveal the numerous evolutionary mechanisms that drove trypsin duplication and divergence during the morphological specialization of cell types and suggest that the secretory cell phenotype is highly adaptable as a vehicle for novel secretory products.

Indexed as

Cell-type specializationCnidarianDomain evolutionNoveltyOrganelle evolutionSecretionTrypsin

Identifiers

PMID31583070
PMCPMC6767649
OpenAlexW2977335136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.