Evidence map›Paper›PMID 31583032›Full record

ArticleDisease markers2019

Haplotypes of

Rasa Liutkeviciene, Alvita Vilkeviciute, Greta Gedvilaite, Kriste Kaikaryte, Loresa Kriauciuniene

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Cells · 2022
    Article
  5. Article
  6. Review
  7. Matrix Metalloproteinases in Age-Related Macular Degeneration (AMD).International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rasa LiutkevicieneNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0001-5395-923X
Alvita VilkeviciuteNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0002-0427-5568
Greta GedvilaiteNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0001-7469-8825
Kriste KaikaryteNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, Kaunas LT-50161, Lithuania.
Loresa KriauciunieneNeuroscience Institute, Lithuanian University of Health Sciences, Medical Academy, Eiveniu 2, Kaunas LT-50161, Lithuania.ORCID https://orcid.org/0000-0001-5849-5323
Lithuanian University of Health Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo determine the impact of

methodsA total of 916 subjects were examined: 309 patients with early AMD, 301 patients with exudative AMD, and 306 healthy controls. The genotyping of

resultsOur study showed that single-nucleotide polymorphisms rs3793784 and rs11200638 were associated with increased odds of early and exudative AMD, and the variant in

conclusionsOur study identified two markers, rs11200638 and rs3793784, as risk factors for early and exudative AMD, and one marker, rs56209061, as a protective factor for early and exudative AMD development. The haplotypes constructed of rs3793784-rs11200638 were found to be associated with AMD development, as well.

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAgedAged, 80 and overAllelesBiomarkersCase-Control StudiesComplement Factor IDNA HelicasesDNA Repair EnzymesFemaleGene ExpressionGene FrequencyHaplotypesHigh-Temperature Requirement A Serine Peptidase 1HumansBiomarkersCFI protein, humanComplement Factor IDNA HelicasesDNA Repair EnzymesERCC6 protein, humanHigh-Temperature Requirement A Serine Peptidase 1HTRA1 protein, humanKCTD10 protein, humanPoly-ADP-Ribose Binding ProteinsPotassium Channels, Voltage-GatedTIMP3 protein, humanTissue Inhibitor of Metalloproteinase-3Vascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID31583032
PMCPMC6754896
OpenAlexW2972834864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.