ArticleDisease markers2019
Ratio of Early Mitral Inflow Velocity to the Global Diastolic Strain Rate and Global Left Ventricular Longitudinal Systolic Strain Predict Overall Mortality and Major Adverse Cardiovascular Events in Hemodialysis Patients.
Article in Disease markers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The association between systolic and diastolic dysfunction and autonomic nervous system function in children receiving chronic hemodialysis.Pediatric nephrology (Berlin, Germany) · 2025Observational
- Zinc Deficiency in Chronic Kidney Disease and Hemodialysis: Insights from Basic Research to Clinical Implications.Nutrients · 2025Review
- The Impact of Age and Sex on Left Ventricular Function Based on Transthoracic Echocardiograms.Reviews in cardiovascular medicine · 2025Article
- A comparative analysis of conventional and speckle-tracking strain echocardiographic findings in diabetic and non-diabetic kidney disease patients with normal ejection fraction.The international journal of cardiovascular imaging · 2023Article
- The diastolic function abnormalities in hemodialysis session: a two-dimensional speckle tracking echocardiographic (2DSTE) study.The international journal of cardiovascular imaging · 2022Article
- Left ventricular strain and left atrial strain are impaired during hemodialysis in children.The international journal of cardiovascular imaging · 2021Article
- Association between Reduced Serum Zinc and Diastolic Dysfunction in Maintenance Hemodialysis Patients.Nutrients · 2021Article
- Frequency and risk factors of impaired left ventricular global longitudinal strain in patients with end-stage renal disease: a two-dimensional speckle-tracking echocardiographic study.Quantitative imaging in medicine and surgery · 2021Article
- The Effect of Hemodialysis-related Volume Changes on Left and Right Ventricle and Left Atrial Function in Dialysis Patients: A Speckle Tracking Echocardiography Study.Journal of cardiovascular echographyArticle
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10 authors.
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Abstract
backgroundThe ratio of early mitral inflow velocity to the global diastolic strain rate (E/E'sr) and global longitudinal systolic strain (GLS) of the left ventricle (LV) are emerging indices of diastolic and systolic functions, respectively, for the LV. Their prognostic significance in the prediction of mortality and cardiovascular (CV) outcomes remains underexplored in hemodialysis (HD) patients.
methodsThis prospective study included 190 maintenance HD patients. The E/E'sr ratio and GLS were assessed using two-dimensional speckle tracking echocardiography. The clinical outcomes included overall mortality, CV mortality, and major adverse cardiovascular events (MACE). The associations between the E/E'sr ratio, GLS, and clinical outcomes were evaluated using multivariate Cox regression analysis. The incremental values of the E/E'sr ratio and GLS in outcome prediction were assessed by
resultsOver a median follow-up period of 3.7 years, there were 35 overall deaths, 16 CV deaths, and 45 MACE. Impaired diastolic function with a higher E/E'sr ratio was associated with overall mortality (HR, 1.484; 95% CI, 1.201-1.834;
conclusionThe E/E'sr ratio and GLS, as emerging indices of LV diastolic and systolic functions, significantly predict mortality and CV outcomes and outperform conventional echocardiographic parameters in outcome prediction in HD patients.
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