Evidence map›Paper›PMID 31582848›Full record

ReviewNature structural & molecular biology2019

RNA-modifying enzymes and their function in a chromatin context.

Konstantinos Tzelepis, Oliver Rausch, Tony Kouzarides

Open access · greenAbstract readReview
In one paragraph

Review in Nature structural & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Review
  3. Emerging roles of RNA mInternational journal of oncology · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Presynaptic Protein Synthesis in Brain Function and Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  10. A non-coding mNature cell biology · 2023
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. RNA m6A methylation regulators in ovarian cancer.Cancer cell international · 2021
    Review
  16. Brain on food: The neuroepigenetics of nutrition.Neurochemistry international · 2021
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Konstantinos TzelepisThe Gurdon Institute and Department of Pathology, University of Cambridge, Cambridge, UK.
Oliver RauschStorm Therapeutics Ltd, Babraham Research Campus, Cambridge, UK.
Tony KouzaridesThe Gurdon Institute and Department of Pathology, University of Cambridge, Cambridge, UK. t.kouzarides@gurdon.cam.ac.uk.ORCID http://orcid.org/0000-0002-8918-4162
University of Cambridge · GB

Funding

Cancer Research UK 17001Cancer Research UK 27321Wellcome Trust 210926Wellcome Trust 210926/Z/18/Z
6 · The paper itself

Abstract

Exciting research has connected specific RNA modifications to chromatin, providing evidence for co-transcriptional deposition and function in gene regulation. Here we review insights gained from studying the co-transcriptional roles of RNA modifications, and their influence in normal and disease contexts. We also discuss how the availability of novel technical approaches could raise the translational potential of targeting RNA-modifying enzymes for the treatment of disease.

Indexed as

RNA Processing, Post-TranscriptionalAnimalsChromatinChromatin Assembly and DisassemblyGene Expression RegulationHumansRNATranscription, GeneticChromatinRNA

Identifiers

PMID31582848
PMCPMC7613430
OpenAlexW2978193699

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.