Evidence map›Paper›PMID 31582812›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2019

Patterns of phlebotomy blood loss and transfusions in extremely low birth weight infants.

Mihai Puia-Dumitrescu, David T Tanaka, Tracy G Spears, Cecil J Daniel, Karan R Kumar, Kamlesh Athavale, Sandra E Juul, P Brian Smith

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06555315 (Pilot Non-inferiority Study Investigating Daily Versus Every Other Day Dosing of Oral Iron in Premature Infants.), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06555315 narecruitingnot on this mapstarted 2024, after this paper: background citation

Pilot Non-inferiority Study Investigating Daily Versus Every Other Day Dosing of Oral Iron in Premature Infants.

TypeinterventionalSponsorCHRISTUS HealthRan2024 to 2026Enrolled100ConditionsVery Low Birth Weight Infant, Premature Infants, Anemia of Prematurity, Iron Deficiency, Anaemia in ChildrenArms6 mg/kg of oral iron as ferrous sulfate administered every other day., 6 mg/kg of oral iron as ferrous sulfate administered every day.
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Minimizing blood sampling in preterm infants.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Continuous transcutaneous COPediatric research · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Minimizing blood sampling in preterm infants.The Cochrane database of systematic reviews · 2024
    Article
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mihai Puia-DumitrescuDepartment of Pediatrics, University of Washington, Seattle, WA, USA.
David T TanakaDepartment of Pediatrics, Duke University Medical Center, Durham, NC, USA.
Tracy G SpearsDuke Clinical Research Institute, Durham, NC, USA.
Cecil J DanielDuke Clinical Research Institute, Durham, NC, USA.
Karan R KumarDepartment of Pediatrics, Duke University Medical Center, Durham, NC, USA.ORCID http://orcid.org/0000-0001-9196-6350
Kamlesh AthavaleDepartment of Pediatrics, Duke University Medical Center, Durham, NC, USA.
Sandra E JuulDepartment of Pediatrics, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6861-6229
P Brian SmithDepartment of Pediatrics, Duke University Medical Center, Durham, NC, USA. brian.smith@duke.edu.
Clinical Research Institute · USDuke Medical Center · USUniversity of Washington · USDuke University · US

Funding

Duke Research Training Program for PediatriciansT32HD043029 · NICHD · DUKE UNIVERSITY · PI BENJAMIN, DANIEL K. · 2002 to 2017
$3.7M
NICHD NIH HHS T32 HD043029
6 · The paper itself

Abstract

objectiveCharacterize frequency and volume of blood draws and transfusions in extremely low birth weight infants in the first 10 weeks of life. STUDY

designWe included infants with a birth weight <1000 g born 23 0/7-29 6/7 weeks gestational age (GA) and with a length of stay ≥10 weeks, admitted between 2014 and 2016 to a single neonatal intensive care unit.

resultsOf 54 infants, median (25th, 75th percentile) GA and birth weight were 25 weeks (24, 26) and 665 g (587, 822), respectively. Median number of blood draws per infant decreased from 57 (49, 65) in week 1 to 12 (8, 22) in week 10. Median volume of blood extracted was 83 mL (70, 97), and median number of blood transfusions was 8 (5, 10).

conclusionsThis cohort experienced a high number and volume of blood draws. Draw frequency and transfusions decreased over the first 10 weeks of life.

Indexed as

Infant, Extremely Low Birth WeightInfant, PrematureAnemiaErythrocyte TransfusionFemaleHumansInfant, Extremely PrematureInfant, NewbornInfant, Premature, DiseasesIntensive Care Units, NeonatalMalePhlebotomy

Identifiers

PMID31582812
PMCPMC7331095
OpenAlexW2978531523

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.