ArticleScientific reports2019
High-resolution Imaging of the Human Cochlea through the Round Window by means of Optical Coherence Tomography.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- A Comprehensive Review on the Optical Micro-Electromechanical Sensors for the Biomedical Application.Frontiers in public health · 2021Pooled it
- Anatomical Integrity of the Human Cochlea Estimated with Optical Coherence Tomography for Future Clinical Application.Journal of the Association for Research in Otolaryngology : JARO · 2026Article
- Anatomical integrity of the human cochlea estimated with optical coherence tomography for future clinical application.bioRxiv : the preprint server for biology · 2025Article
- Human inner ear fluid imbalance detected by optical coherence tomography correlates with hearing loss.Science translational medicine · 2025Article
- Imaging theJournal of biomedical optics · 2025Article
- Immuno-surveillance and protection of the human cochlea.Frontiers in neurology · 2024Article
- Examining the utility of near infrared light as pre-exposure therapy to mitigate temporary noise-induced hearing loss in humans.Frontiers in neurology · 2024Article
- Dynamic micro-optical coherence tomography enables structural and metabolic imaging of the mammalian cochlea.Frontiers in molecular neuroscience · 2024Article
- Conserved features of eye movement related eardrum oscillations (EMREOs) across humans and monkeys.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Optical Coherence Tomography-Based Atlas of the Human Cochlear Hook Region.Journal of clinical medicine · 2022Article
- An optically-guided cochlear implant sheath for real-time monitoring of electrode insertion into the human cochlea.Scientific reports · 2022Article
- Article
- Optical coherence tomography's current clinical medical and dental applications: a review.F1000Research · 2021Review
- In Vivo Cochlear imaging provides a tool to study endolymphatic hydrops.Journal of vestibular research : equilibrium & orientation · 2021Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human cochlea is deeply embedded in the temporal bone and surrounded by a thick otic capsule, rendering its internal structure inaccessible for direct visualization. Clinical imaging techniques fall short of their resolution for imaging of the intracochlear structures with sufficient detail. As a result, there is a lack of knowledge concerning best practice for intracochlear therapy placement, such as cochlear implantation. In the past decades, optical coherence tomography (OCT) has proven valuable for non-invasive, high-resolution, cross-sectional imaging of tissue microstructure in various fields of medicine, including ophthalmology, cardiology and dermatology. There is an upcoming interest for OCT imaging of the cochlea, which so far was mostly carried out in small animals. In this temporal bone study, we focused on high-resolution imaging of the human cochlea. The cochlea was approached through mastoidectomy and posterior tympanotomy, both standard surgical procedures. A commercially available spectral-domain OCT imaging system was used to obtain high-resolution images of the cochlear hook region through the intact round window membrane in four cadaveric human temporal bones. We discuss the qualitative and quantitative characteristics of intracochlear structures on OCT images and their importance for cochlear implant surgery.
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