Evidence map›Paper›PMID 31582195›Full record

Trial reportThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2019

Negative Emotions and the Course of Depression During Psychotherapy in Suicidal Older Adults With Depression and Cognitive Impairment.

Elizabeth Arslanoglou, Samprit Banerjee, Joanna Pantelides, Laurie Evans, Dimitris N Kiosses

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Problem Adaptation Therapy (PATH): Origins, Current Status, and Future Directions.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2022
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elizabeth ArslanoglouWeill-Cornell Institute of Geriatric Psychiatry (EA, SB, JP, LE, DNK), Weill Cornell Medicine, White Plains, NY.
Samprit BanerjeeWeill-Cornell Institute of Geriatric Psychiatry (EA, SB, JP, LE, DNK), Weill Cornell Medicine, White Plains, NY.
Joanna PantelidesWeill-Cornell Institute of Geriatric Psychiatry (EA, SB, JP, LE, DNK), Weill Cornell Medicine, White Plains, NY.
Laurie EvansWeill-Cornell Institute of Geriatric Psychiatry (EA, SB, JP, LE, DNK), Weill Cornell Medicine, White Plains, NY.
Dimitris N KiossesWeill-Cornell Institute of Geriatric Psychiatry (EA, SB, JP, LE, DNK), Weill Cornell Medicine, White Plains, NY. Electronic address: dkiosses@med.cornell.edu.
Cornell University · USWeill Cornell Medicine · US

Funding

Research Methods CoreP30MH085943 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2009 to 2013
$9.2M
Relief: A Behavioral Intervention for Depression and Chronic Pain for Primary Care PracticesP50MH113838 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI ALEXOPOULOS, GEORGE S · 2017 to 2020
$5.7M
A Novel Cognitive Reappraisal Intervention for Suicide PreventionR33MH110542 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2018 to 2022
$2.2M
Home-Delivered Intervention for Depressed, Cognitively Impaired EldersR01MH091045 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2011 to 2015
$1.8M
A Novel Cognitive Reappraisal Intervention for Suicide PreventionR61MH110542 · NIMH · WEILL MEDICAL COLL OF CORNELL UNIV · PI KIOSSES, DIMITRIS N · 2016 to 2017
$1.2M
NIMH NIH HHS P30 MH085943NIMH NIH HHS P50 MH113838NIMH NIH HHS R01 MH091045NIMH NIH HHS R33 MH110542NIMH NIH HHS R61 MH110542
6 · The paper itself

Abstract

objectiveThe study examines the relationship of negative emotions with: 1) non-emotional symptoms (e.g., vegetative and physical symptoms) and 2) the course of depression in suicidal older adults with Major Depressive Disorder (MDD) and cognitive impairment treated with psychotherapy.

designThe authors identified a subgroup of participants (N = 26) who expressed suicidal ideation at Baseline or Week 12 from a randomized controlled trial (RCT) of two psychosocial interventions, Problem Adaptation Therapy (PATH) and Supportive Therapy for Cognitively Impaired. The authors assessed negative emotions, non-emotional symptoms of depression, depression severity, and suicidal ideation at entry, week 4, week 8, and week 12.

participantsParticipants were 65 years and older and had a diagnosis of unipolar depression, varying degrees of cognitive impairment (up to moderate dementia) and suicidal ideation.

settingThe study was conducted in the Outpatient Department of New York Presbyterian/Weill Cornell Medicine in Westchester, NY. MEASUREMENTS: Negative emotions and non-emotional items were identified with the 24-item Hamilton Depression Rating Scale (Ham-D).

resultsAmong participants with suicidal ideation, the reduction in negative emotions from baseline to week 4, week 4 to week 8, and week 8 to week 12 was significantly associated with the reduction in non-emotional symptoms of depression at weeks 4, 8, and 12 (F

conclusionOur findings may guide the treatment of older patients with depression and suicidal ideation to help reduce depression and suicide risk.

Indexed as

PsychotherapySuicidal IdeationAgedAged, 80 and overCognitive DysfunctionDepressionEmotionsFemaleHumansMajor Depressive DisorderMaleSeverity of Illness Indexcognitive impairmentdepressionelderlynegative emotionsSuicide/self-harm

Identifiers

PMID31582195
PMCPMC6985925
OpenAlexW2970975020

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.