Evidence map›Paper›PMID 31582182›Full record

ArticleBiophysical journal2019

Disulfide Chaperone Knockouts Enable In Vivo Double Spin Labeling of an Outer Membrane Transporter.

Thushani D Nilaweera, David A Nyenhuis, Robert K Nakamoto, David S Cafiso

Open access · greenAbstract read
In one paragraph

Article in Biophysical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Synthesis and Properties of (1International journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Thushani D NilaweeraDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia.
David A NyenhuisDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia.
Robert K NakamotoDepartment of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia.
David S CafisoDepartment of Chemistry and Center for Membrane Biology, University of Virginia, Charlottesville, Virginia. Electronic address: cafiso@virginia.edu.
University of Virginia · US

Funding

MOLECULAR MECHANISMS OF MEMBRANE TRANSPORTR01GM035215 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI DAVID S CAFISO · 1985 to 2026
$7.3M
Training in Molecular BiophysicsT32GM080186 · NIGMS · UNIVERSITY OF VIRGINIA · PI NAKAMOTO, ROBERT K. · 2008 to 2019
$1.5M
NIGMS NIH HHS R01 GM035215NIGMS NIH HHS T32 GM080186
6 · The paper itself

Abstract

Recent advances in the application of electron paramagnetic resonance spectroscopy have demonstrated that it is possible to obtain structural information on bacterial outer membrane (OM) proteins in intact cells from extracellularly labeled cysteines. However, in the Escherichia coli OM B

Indexed as

Bacterial Outer Membrane ProteinsBacterial ProteinsCysteineDisulfidesElectron Spin Resonance SpectroscopyEscherichia coli ProteinsLoss of Function MutationMembrane ProteinsMembrane Transport ProteinsProtein Disulfide-IsomerasesBacterial Outer Membrane ProteinsBacterial ProteinsBtuB protein, E coliCysteineDisulfidesdsbA protein, E coliDsbB protein, BacteriaEscherichia coli ProteinsMembrane ProteinsMembrane Transport ProteinsProtein Disulfide-Isomerases

Identifiers

PMID31582182
PMCPMC6817557
OpenAlexW2972742428

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.