Evidence map›Paper›PMID 31581717›Full record

ArticleToxins2019

Determination of Selected Isoquinoline Alkaloids from

Anna Petruczynik, Tomasz Plech, Tomasz Tuzimski, Justyna Misiurek, Barbara Kaproń, Dorota Misiurek, Małgorzata Szultka-Młyńska, Bogusław Buszewski, Monika Waksmundzka-Hajnos

Open access · goldAbstract readComparative Study
In one paragraph

Article in Toxins, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Genetic Stability and Photosystem II Functioning of In Vitro-RecoveredInternational journal of molecular sciences · 2025
    Article
  3. Plants (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Determination of Selected Isoquinoline Alkaloids fromInternational journal of molecular sciences · 2023
    Article
  7. Article
  8. Isoquinoline Alkaloid Contents inMolecules (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Shoot Tip Cryopreservation ofInternational journal of molecular sciences · 2020
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Anna PetruczynikDepartment of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a 20-093 Lublin, Poland. annapetruczynik@poczta.onet.pl.
Tomasz PlechDepartment of Pharmacology, Medical University of Lublin, Chodźki 4a 20-093 Lublin, Poland. tomasz.plech@umlub.pl.
Tomasz TuzimskiDepartment of Physical Chemistry, Medical University of Lublin, Chodźki 4a 20-093 Lublin, Poland. tomasz.tuzimski@umlub.pl.
Justyna MisiurekDepartment of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a 20-093 Lublin, Poland. justyna.misiurek@umlub.pl.
Barbara KaprońDepartment of Clinical Genetics, Medical University of Lublin, Radziwiłłowska 11, 20-080 Lublin, Poland. barbara.kapron@umlub.pl.
Dorota MisiurekBotanical Garden of Maria Curie-Skłodowska University in Lublin, Sławinkowska 3, 20-810 Lublin, Poland. dorota.misiurek@poczta.umcs.lublin.pl.
Małgorzata Szultka-MłyńskaDepartment of Environmental Chemistry and Bioanalytics, Nicolaus Copernicus University, Faculty of Chemistry Gagarina 7, PL-87-100 Torun, Poland. szultka.malgorzata@wp.pl.
Bogusław BuszewskiDepartment of Environmental Chemistry and Bioanalytics, Nicolaus Copernicus University, Faculty of Chemistry Gagarina 7, PL-87-100 Torun, Poland. bbusz@chem.umk.pl.
Monika Waksmundzka-HajnosDepartment of Inorganic Chemistry, Medical University of Lublin, Chodźki 4a 20-093 Lublin, Poland. monika.hajnos@umlub.pl.
Medical University of Lublin · PLNicolaus Copernicus University · PLMaria Curie-Skłodowska University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alkaloids have protective functions for plants and can play an important role in living organisms. Alkaloids may have a wide range of pharmacological activities. Many of them have cytotoxic activity. Nowadays, cancer has become a serious public health problem. Searching for effective drugs with anticancer activity is one of the most significant challenges of modern scientific research. The aim of this study was the investigation of cytotoxic activity of extracts obtained from

Indexed as

AlkaloidsAntineoplastic AgentsIsoquinolinesMagnoliopsidaPlant ExtractsCell Line, TumorCell ProliferationCell SurvivalChromatography, High Pressure LiquidHumansTandem Mass SpectrometryAlkaloidsAntineoplastic AgentsIsoquinolinesPlant ExtractsCorydalis luteacytotoxic activityDicentra spectabilisFumaria officinalisHPLC-DADisoquinoline alkaloidsMacleaya cordataMahonia aquifoliaMeconopsis cambrica

Identifiers

PMID31581717
PMCPMC6832497
OpenAlexW2977536817

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.