Evidence map›Paper›PMID 31581716›Full record

ArticleJournal of clinical medicine2019

Early Detection of Bacteraemia Using Ten Clinical Variables with an Artificial Neural Network Approach.

Kyoung Hwa Lee, Jae June Dong, Su Jin Jeong, Myeong-Hun Chae, Byeong Soo Lee, Hong Jae Kim, Sung Hun Ko, Young Goo Song

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyoung Hwa LeeDivision of Infectious Diseases, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea. khlee0309@yuhs.ac.ORCID 0000-0003-0033-1398
Jae June DongDepartment of Family Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06273, Korea. s82tonight@yuhs.ac.
Su Jin JeongDivision of Infectious Diseases, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea. JSJ@yuhs.ac.
Myeong-Hun ChaeSelvas Artificial Intelligence Incorporate, Seoul 08594, Korea. victor.m.chae@selvas.com.
Byeong Soo LeeSelvas Artificial Intelligence Incorporate, Seoul 08594, Korea. jacob.b.lee@selvas.com.
Hong Jae KimDepartment of Medical Information, Gangnam Severance Hospital, Seoul 06273, Korea. khj1123@yuhs.ac.
Sung Hun KoDepartment of Medical Information, Gangnam Severance Hospital, Seoul 06273, Korea. ydhun05@yuhs.ac.
Young Goo SongDivision of Infectious Diseases, Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 06273, Korea. imfell@yuhs.ac.ORCID 0000-0002-0733-4156

Funding

Korean Health Technology Research & Development Project, Ministry of Health & Welfare, Republic of Korea HI18C0718
6 · The paper itself

Abstract

An adequate model for predicting bacteraemia has not yet been developed. This study aimed to evaluate the performance of an artificial neural network (ANN)-based prediction model in comparison with previous statistical models. The performance of multi-layer perceptron (MLP), a representative ANN model, was verified via comparison with a non-neural network model. A total of 1260 bacteraemia episodes were identified in 13,402 patients. In MLP with 128 hidden layer nodes, the area under the receiver operating characteristic curve (AUC) of the prediction performance was 0.729 (95% confidence interval [CI]; 0.712-0.728), while in MLP with 256 hidden layer nodes, it was 0.727 (95% CI; 0.713-0.727). In a conventional Bayesian statistical method, the AUC was 0.7. The aforementioned two MLP models exhibited the highest sensitivity (0.810). The ranking of clinical variables was used to describe the influential power of the prediction. Serum alkaline phosphatase was one of the most influential clinical variables, and one-out search was the best ranking method for measuring the influence of the clinical variables. Furthermore, adding variables beyond the 10 top-ranking ones did not significantly affect the prediction of bacteraemia. The ANN model is not inferior to conventional statistical approaches. Bacteraemia can be predicted using only the top 10 clinical variables determined by a ranking method, and the model can be used in clinical practice by applying real-time monitoring.

Indexed as

artificial intelligenceartificial neural networkbacteraemiamachine learningprediction

Identifiers

PMID31581716
PMCPMC6832527

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.