Evidence map›Paper›PMID 31581705›Full record

ArticleBiomolecules2019

Linking Dysregulated AMPK Signaling and ER Stress in Ethanol-Induced Liver Injury in Hepatic Alcohol Dehydrogenase Deficient Deer Mice.

Mukund P Srinivasan, Kamlesh K Bhopale, Samir M Amer, Jie Wan, Lata Kaphalia, Ghulam S Ansari, Bhupendra S Kaphalia

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  10. An Overview of the Mechanism ofEvidence-based complementary and alternative medicine : eCAM · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mukund P SrinivasanDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Kamlesh K BhopaleDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Samir M AmerDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Jie WanDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Lata KaphaliaDivision of Pulmonary, Critical Care Medicine, Department of Internal Medicine, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Ghulam S AnsariDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Bhupendra S KaphaliaDepartment of Pathology, The University of Texas Medical Branch, Galveston, TX 77555, USA. bkaphali@utmb.edu.
The University of Texas Medical Branch at Galveston · USTanta University · EG

Funding

AMPK Signaling and Chronic Alcoholic PancreatitisR21AA024699 · NIAAA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI KAPHALIA, BHUPENDRA S · 2016 to 2017
$407k
6 · The paper itself

Abstract

Ethanol (EtOH) metabolism itself can be a predisposing factor for initiation of alcoholic liver disease (ALD). Therefore, a dose dependent study to evaluate liver injury was conducted in hepatic alcohol dehydrogenase (ADH) deficient (ADH

Indexed as

Alanine TransaminaseAlcohol DehydrogenaseAMP-Activated Protein KinasesAnimalsBlood Alcohol ContentDisease Models, AnimalEndoplasmic Reticulum StressEthanolGene Knockout TechniquesLipid MetabolismLiverLiver Diseases, AlcoholicMaleMiceSignal TransductionAlanine TransaminaseAlcohol DehydrogenaseAMP-Activated Protein KinasesBlood Alcohol ContentEthanolalcohol dehydrogenasealcoholic liver diseaseAMPK signalingdeer miceER stress

Identifiers

PMID31581705
PMCPMC6843321
OpenAlexW2977338267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.