Evidence map›Paper›PMID 31581581›Full record

ArticleBiomolecules2019

Characterization of the Anti-Cancer Activity of the Probiotic Bacterium

Joo-Eun Lee, Jina Lee, Ji Hyun Kim, Namki Cho, Sung Hoon Lee, Sung Bum Park, Byumseok Koh, Dukjin Kang, Seil Kim, Hee Min Yoo

Open access · goldAbstract readComparative Study
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
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  8. Evaluation ofInternational journal of molecular and cellular medicine · 2025
    Article
  9. Review
  10. Advancements in 3D In Vitro Models for Colorectal Cancer.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Bones and guts - Why the microbiome matters.Journal of bone oncology · 2024
    Article
  15. Male-Biased Gut Microbiome and Metabolites Aggravate Colorectal Cancer Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  16. Lactobacillus for ribosome peptide editing cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Joo-Eun LeeStem Cell Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea. jooeunlee@kribb.re.kr.
Jina LeeCenter for Bioanalysis, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea. jalee@kriss.re.kr.
Ji Hyun KimCenter for Bioanalysis, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea. jhk0709@kriss.re.kr.
Namki ChoCollege of Pharmacy and Research Institute of Drug Development, Chonnam National University, Gwangju 61186, Korea. cnamki@chonnam.ac.kr.
Sung Hoon LeeCollege of Pharmacy, Chung-Ang University, Seoul 06974, Korea. sunghoonlee@cau.ac.kr.
Sung Bum ParkTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Korea. spark@krict.re.kr.
Byumseok KohTherapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Korea. bkoh@krict.re.kr.
Dukjin KangCenter for Bioanalysis, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea. djkang@kriss.re.kr.
Seil KimCenter for Bioanalysis, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea. stapler@kriss.re.kr.
Hee Min YooCenter for Bioanalysis, Korea Research Institute of Standards and Science (KRISS), Daejeon 34113, Korea. hmy@kriss.re.kr.
Korea Research Institute of Standards and Science · KRKorea Research Institute of Chemical Technology · KRChonnam National University · KRChung-Ang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to investigate the potential anti-cancer effects of probiotic cell-free supernatant (CFS) treatment using

Indexed as

bcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinBH3 Interacting Domain Death Agonist ProteinBiological ProductsCell Culture TechniquesCell Line, TumorCell ProliferationCell SurvivalColorectal NeoplasmsGene Expression Regulation, NeoplasticHCT116 CellsHT29 CellsHumansLimosilactobacillus fermentumProbioticsProto-Oncogene Proteins c-bcl-2BAK1 protein, humanBAX protein, humanbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinBH3 Interacting Domain Death Agonist ProteinBID protein, humanBiological ProductsPMAIP1 protein, humanProto-Oncogene Proteins c-bcl-23D cultureapoptosiscolorectal cancerLactobacillus fermentumprobioticsspheroid

Identifiers

PMID31581581
PMCPMC6843223
OpenAlexW2977416734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.