Evidence map›Paper›PMID 31581577›Full record

ArticleBiomolecules2019

Pharmacophore Directed Screening of Agonistic Natural Molecules Showing Affinity to 5HT

Ganesh Kumar Veeramachaneni, V B S C Thunuguntla, Maharshi Bhaswant, Michael L Mathai, Jayakumar Singh Bondili

Open access · goldAbstract read
In one paragraph

Article in Biomolecules, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. "Selective" serotonin 5-HTBiochemical pharmacology · 2022
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ganesh Kumar VeeramachaneniDepartment of Biotechnology, Koneru Lakshmaiah Education Foundation (KLEF), Green Fields, Vaddeswaram, Guntur (Dt.) A.P. 522 502, India. ganesh.vgk55@gmail.com.
V B S C ThunuguntlaInstitute of Health and Sport, Victoria University, Melbourne 3011, Australia. venkata.thunuguntla@live.vu.edu.au.
Maharshi BhaswantMolecular Nanomedicine Research Unit, Centre for Nanoscience and Nanotechnology, Sathyabama Institute of Science and Technology, Chennai 600 119, India. cmaharshi@gmail.com.
Michael L MathaiInstitute of Health and Sport, Victoria University, Melbourne 3011, Australia. Michael.Mathai@vu.edu.au.
Jayakumar Singh BondiliDepartment of Biotechnology, Koneru Lakshmaiah Education Foundation (KLEF), Green Fields, Vaddeswaram, Guntur (Dt.) A.P. 522 502, India. jksingh@kluniversity.in.
Koneru Lakshmaiah Education Foundation · INVictoria University · AUSathyabama Institute of Science and Technology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity prevalence continues to be a foremost health concern across the globe leading to the development of major health risk conditions like type II diabetes, hyperlipidemia, hypertension and even cancers. Because of the deprived drug-based management system, there is an urgent need for the development of new drugs aiming at satiety and appetite control targets. Among the reported satiety signaling targets, 5HT

Indexed as

AsparagineBinding SitesBiological ProductsComputer SimulationDrug DesignHumansModels, MolecularMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsZincAsparagineBiological ProductsHTR2C protein, humanReceptor, Serotonin, 5-HT2CSerotonin 5-HT2 Receptor AgonistsZinc5HT2C receptordynamic simulations.glidepharmacophore modelingZINC natural molecule database

Identifiers

PMID31581577
PMCPMC6843766
OpenAlexW2977310992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.