Evidence map›Paper›PMID 31581550›Full record

ArticleFoods (Basel, Switzerland)2019

Oligosaccharides Isolated from MGO™ Manuka Honey Inhibit the Adhesion of

Jonathan A Lane, Julie Calonne, Helen Slattery, Rita M Hickey

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  7. Chemical Composition and the Anticancer, Antimicrobial, and Antioxidant Properties ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  8. Article
  9. The Feasibility of Utilizing CulturedJournal of fungi (Basel, Switzerland) · 2021
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jonathan A LaneTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork P61 C996, Ireland. jonathan.lane.0@gmail.com.
Julie CalonneDepartment of Biological Sciences, Cork Institute of Technology, Cork T12 P928, Ireland. helen.slattery@teagasc.ie.
Helen SlatteryTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork P61 C996, Ireland. july.c@hotmail.fr.
Rita M HickeyTeagasc Food Research Centre, Moorepark, Fermoy, Co. Cork P61 C996, Ireland. rita.hickey@teagasc.ie.
Teagasc - The Irish Agriculture and Food Development Authority · IEMunster Technological University · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Historically, honey is known for its anti-bacterial and anti-fungal activities and its use for treatment of wound infections. Although this practice has been in place for millennia, little information exists regarding which manuka honey components contribute to the protective nature of this product. Given that sugar accounts for over 80% of honey and up to 25% of this sugar is composed of oligosaccharides, we have investigated the anti-infective activity of manuka honey oligosaccharides against a range of pathogens. Initially, oligosaccharides were extracted from a commercially-available New Zealand manuka honey-MGO™ Manuka Honey (Manuka Health New Zealand Ltd)-and characterized by High pH anion exchange chromatography coupled with pulsed amperiometric detection. The adhesion of specific pathogens to the human colonic adenocarcinoma cell line, HT-29, was then assessed in the presence and absence of these oligosaccharides. Manuka honey oligosaccharides significantly reduced the adhesion of

Indexed as

anti-adhesionEscherichia coliManuka honeyoligosaccharidesPseudomonas aeruginosaStaphylococcus aureus

Identifiers

PMID31581550
PMCPMC6835506
OpenAlexW2978652590

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.