Evidence map›Paper›PMID 31581497›Full record

ReviewPharmaceutics2019

Recent Developments in the Reduction of Oxidative Stress through Antioxidant Polymeric Formulations.

Muhammad Shajih Zafar, Alessandra Quarta, Marco Marradi, Andrea Ragusa

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Passion fruit (Frontiers in nutrition · 2024
    Pooled it
  2. Review
  3. Active Polysaccharide Films IncorporatingMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Study onPharmaceutics · 2020
    Article
  20. NovelAntioxidants (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Muhammad Shajih ZafarDepartment of Engineering for Innovation, University of Salento, via Monteroni, 73100 Lecce, Italy. shajihengr@gmail.com.
Alessandra QuartaCNR Nanotec, Institute of Nanotechnology, via Monteroni, 73100 Lecce, Italy. alessandra.quarta@nanotec.cnr.it.
Marco MarradiDepartment of Chemistry "Ugo Schiff", University of Florence, via della Lastruccia 13, 50019 Sesto Fiorentino, Firenze, Italy. marco.marradi@unifi.it.
Andrea RagusaDepartment of Engineering for Innovation, University of Salento, via Monteroni, 73100 Lecce, Italy. andrea.ragusa@unisalento.it.
University of Salento · ITIstituto Nanoscienze · ITUniversity of Florence · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reactive oxygen and nitrogen species (RONS) are produced endogenously in our body, or introduced through external factors, such as pollution, cigarette smoke, and excessive sunlight exposure. In normal conditions, there is a physiological balance between pro-oxidant species and antioxidant molecules that are able to counteract the detrimental effect of the former. Nevertheless, when this homeostasis is disrupted, the resulting oxidative stress can lead to several pathological conditions, from inflammation to cancer and neurodegenerative diseases. In this review, we report on the recent developments of different polymeric formulations that are able to reduce the oxidative stress, from natural extracts, to films and hydrogels, and finally to nanoparticles (NPs).

Indexed as

antioxidantchitosanextractfilmhydrogelnanoparticlepolymerradicalsROS

Identifiers

PMID31581497
PMCPMC6835330
OpenAlexW2979140182

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.