Evidence map›Paper›PMID 31581341›Full record

ArticlePhotochemistry and photobiology2020

Weather-informed Light-tissue Model-Based Dose Planning for Indoor Daylight Photodynamic Therapy.

Ethan P M LaRochelle, Michael Shane Chapman, Edward V Maytin, Tayyaba Hasan, Brian W Pogue

Abstract read
In one paragraph

Article in Photochemistry and photobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ethan P M LaRochelleThayer School of Engineering, Dartmouth College, Hanover, NH.ORCID 0000-0002-7883-9987
Michael Shane ChapmanDepartment of Surgery, Geisel School of Medicine, Dartmouth College, Lebanon, NH.
Edward V MaytinDepartment of Biomedical Engineering, Cleveland Clinic, Cleveland, OH.
Tayyaba HasanWellman Center for Photomedicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Brian W PogueThayer School of Engineering, Dartmouth College, Hanover, NH.

Funding

Small Molecule Enhancers of Photodynamic Therapy for Skin CancerP01CA084203 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI Brian William Pogue · 2001 to 2026
$27.9M
NCI NIH HHS P01 CA084203
6 · The paper itself

Abstract

Daylight activation for photodynamic therapy (PDT) of skin lesions is now widely adopted in many countries as a less painful and equally effective treatment mechanism, as compared to red or blue light activation. However, seasonal daylight availability and transient weather conditions complicate light dose estimations. A method is presented for dose planning without placing a large burden on clinical staff, by limiting spectral measurements to a one-time site assessment, and then using automatically acquired weather reports to track transient conditions. The site assessment tools are used to identify appropriate treatment locations for the annual and daily variations in sunlight exposure for clinical center planning. The spectral information collected from the site assessment can then be integrated with real-time daily electronic weather data. It was shown that a directly measured light exposure has strong correlation (R

Indexed as

LightModels, TheoreticalWeatherDose-Response Relationship, DrugDose-Response Relationship, RadiationHumansPhotochemotherapyPhotosensitizing AgentsSunlightPhotosensitizing Agents

Identifiers

PMID31581341
PMCPMC7117968

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.