ArticleJournal of animal science2019
Immune competence traits assessed during the stress of weaning are heritable and favorably genetically correlated with temperament traits in Angus cattle1.
Article in Journal of animal science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- A systematic review with meta-analysis of heritability estimates for temperament-related traits in beef and dairy cattle populations.Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · 2025Pooled it
- Polymorphisms in IRF3 exon 1 influence the immune response to Brucella infection in small ruminants.Mammalian genome : official journal of the International Mammalian Genome Society · 2026Article
- Immunological studies on new rabbit paternal lines with different potentials for growth rate and resilience: pathways towards healthier animals.Veterinary research · 2025Article
- The genetic relationship between immune competence traits and micro-genetic environmental sensitivity of weight, fat, and muscle traits in Australian Angus cattle.Genetics, selection, evolution : GSE · 2025Article
- Single-cell transcriptomics uncovers key immune drivers of vaccine efficacy in cattle.BMC genomics · 2025Article
- Circulating microRNAs associated with immune competence in Angus cattle.Journal of animal science · 2025Article
- Genetic estimates and genome-wide association studies of antibody response in Tanzanian dairy cattle.Frontiers in genetics · 2025Article
- Characterization of the Temperament and Reactivity of Nelore Cattle (Animals : an open access journal from MDPI · 2024Article
- Genetic diversity and phylogenetic relationship of Angus herds in Hungary and analyses of their production traits.Animal bioscience · 2024Article
- Aleutian disease: Risk factors and ImmunAD strategy for genetic improvement of tolerance in American mink (Neogale vison).PloS one · 2024Article
- Review
- Deletion in KARLN intron 5 and predictive relationship with bovine tuberculosis and brucellosis infection phenotype.Veterinary research communications · 2023Article
- Unraveling the phenotypic and genomic background of behavioral plasticity and temperament in North American Angus cattle.Genetics, selection, evolution : GSE · 2023Article
- The effects of timing of high immune response phenotyping in relation to weaning on immune responses of crossbred beef calves.Journal of animal science · 2023Article
- Article
- The innate immune stimulant Amplimune® is safe to administer to young feedlot cattle.Australian veterinary journal · 2022Article
- Immuno-phenotyping of Canadian beef cattle: adaptation of the high immune response methodology for utilization in beef cattle.Translational animal science · 2022Article
- ImmuneDEX: a strategy for the genetic improvement of immune competence in Australian Angus cattle.Journal of animal science · 2021Article
- Associations between immune competence phenotype and feedlot health and productivity in Angus cattle.Journal of animal science · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Selection for production traits with little or no emphasis on health-related traits has the potential to increase susceptibility to disease in food-producing animals. A possible genetic strategy to mitigate such effects is to include both production and health traits in the breeding objective when selecting animals. For this to occur, reliable methodologies are required to assess beneficial health traits, such as the immune capacity of animals. We describe here a methodology to assess the immune competence of beef cattle which is both practical to apply on farm and does not restrict the future sale of tested animals. The methodology also accommodates variation in prior vaccination history of cohorts of animals being tested. In the present study, the immune competence phenotype of 1,100 Angus calves was assessed during yard weaning. Genetic parameters associated with immune competence traits were estimated and associations between immune competence, temperament, and stress-coping ability traits were investigated. Results suggested that immune competence traits, related to an animal's ability to mount both antibody and cell-mediated immune responses, are moderately heritable (h2 = 0.32 ± 0.09 and 0.27 ± 0.08, respectively) and favorably genetically correlated with the temperament trait, flight time (r = 0.63 ± 0.31 and 0.60 ± 0.29 with antibody and cell-mediated immune responses, respectively). Development of methodologies to assess the immune competence phenotype of beef cattle is a critical first step in the establishment of genetic selection strategies aimed at improving the general disease resistance of beef herds. Strategies aimed at reducing the incidence of disease in beef cattle are expected to significantly improve animal health and welfare, reduce reliance on the use of antibiotics to treat disease, and reduce disease-associated costs incurred by producers.
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