Evidence map›Paper›PMID 31581256›Full record

ArticlePloS one2019

Testing gene by community disadvantage moderation of sexual health outcomes among urban women.

Terrinieka W Powell, Jill A Rabinowitz, Michelle R Kaufman, Adam J Milam, Kelly Benke, Danielle Y Sisto, George Uhl, Brion S Maher, Nicholas S Ialongo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Terrinieka W PowellDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Jill A RabinowitzDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.ORCID 0000-0002-3674-8032
Michelle R KaufmanDepartment of Health, Behavior and Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Adam J MilamDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Kelly BenkeDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Danielle Y SistoDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
George UhlNew Mexico VA HealthCare System, Las Vegas, NM, United States of America.
Brion S MaherDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.
Nicholas S IalongoDepartment of Population, Family and Reproductive Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, United States of America.

Funding

NIDA Epidemiology Training Program: Johns Hopkins UniversityT32DA007292 · NIDA · JOHNS HOPKINS UNIVERSITY · PI RENEE M. JOHNSON, Brion S Maher · 1993 to 2026
$17.7M
TRANSITIONS INTO ADULTHOOD--THE BALTIMORE STUDYR01DA009897 · NIDA · JOHNS HOPKINS UNIVERSITY · PI EATON, WILLIAM W · 1997 to 2011
$4.4M
PERIODIC FOLLOW UP OF TWO UNIVERSAL PREVENTIVE TRIALSR01MH057005 · NIMH · JOHNS HOPKINS UNIVERSITY · PI IALONGO, NICHOLAS S · 1998 to 2007
$4.2M
HIV Intervention Science Training Program for Underserved Investigators R25MH080665 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI EL-BASSEL, NABILA, WU, ELWIN · 2007 to 2023
$2.8M
Center for Adolescent Health Promotion and Disease Prev*U48DP000040 · DP · JOHNS HOPKINS UNIVERSITY · PI SONENSTEIN, FREYA L · 2004 to 2008
$2.2M
A library-based prevention intervention for adolescents affected by parental drug use K01DA042134 · NIDA · JOHNS HOPKINS UNIVERSITY · PI POWELL, TERRINIEKA WILLIAMS · 2017 to 2022
$1.0M
mHealth Intervention via Mentors: Preventing Substance Use, Sexual Risk and Violence among Inner City Youth through Technology-Enhanced MentoringK01DA042138 · NIDA · JOHNS HOPKINS UNIVERSITY · PI KAUFMAN, MICHELLE R. · 2017 to 2021
$896k
Genes, Environment and Drug Use in Three Baltimore CohortsR01DA036525 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MAHER, BRION S · 2015 to 2017
$727k
NCCDPHP CDC HHS U48 DP000040NIDA NIH HHS K01 DA042134NIDA NIH HHS K01 DA042138NIDA NIH HHS R01 DA009897NIDA NIH HHS R01 DA036525NIDA NIH HHS T32 DA007292NIMH NIH HHS R01 MH057005NIMH NIH HHS R25 MH080665
6 · The paper itself

Abstract

We examined whether the interplay between community disadvantage and a conduct disorder polygenic risk score (CD PRS) was associated with sexual health outcomes among urban women. Participants (N = 511; 75.5% African American) were originally recruited to participate in a school-based intervention and were followed into adulthood. Community disadvantage was calculated using census data when participants were in first grade. At age 20, blood or saliva samples were collected and participants reported on their condom use, sexual partners, and sexually transmitted infections. A CD PRS was created based on a genome-wide association study conducted by Dick et al. [2010]. Higher levels of community disadvantage was associated with greater sexually transmitted infections among women with a higher CD PRS. Implications of the study findings are discussed.

Indexed as

Genetic TestingSexual HealthUrban HealthUrban Health ServicesWomen's HealthWomen's Health ServicesFemaleGenetic Predisposition to DiseaseHumansMultifactorial InheritanceOdds RatioOutcome Assessment, Health Care

Identifiers

PMID31581256
PMCPMC6776350

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.