ArticleMMWR. Morbidity and mortality weekly report2019
National Trends in Hepatitis C Infection by Opioid Use Disorder Status Among Pregnant Women at Delivery Hospitalization - United States, 2000-2015.
Article in MMWR. Morbidity and mortality weekly report, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 50 citations in OpenAlex.
- Partnerships With Health Plans to Link Data From Electronic Health Records to Claims for Research Using PCORnet®.Medical care · 2026Article
- Cost-Effectiveness of Treatment for Opioid Use Disorder in Pregnancy and Its Impact on Birth Outcomes.JAMA pediatrics · 2025Article
- The Effect of HCV on Methadone Dose During Pregnancy.Journal of viral hepatitis · 2025Article
- Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cell infiltration.Frontiers in cellular and infection microbiology · 2025Article
- Differences in hepatitis C virus (HCV) testing and treatment by opioid, stimulant, and polysubstance use among people who use drugs in rural U.S. communities.Harm reduction journal · 2024Article
- Postpartum Access to Health Care and Opioid Use Treatment: An Evaluation of a Medicaid Population.North Carolina medical journal · 2024Article
- Trends in the Prevalence of Hepatitis C Infection During Pregnancy and Maternal-Infant Outcomes in the US, 1998 to 2018.JAMA network open · 2023Article
- Clinician barriers, perceptions, and practices in treating patients with hepatitis C virus and substance use disorder in the United States.Preventive medicine reports · 2023Article
- Evidence for Implementation: HIV/HCV Coinfection and Pregnancy.Current HIV/AIDS reports · 2023Review
- Maternal hepatitis C prevalence and trends by county, US: 2016-2020.Paediatric and perinatal epidemiology · 2023Article
- Maternal hepatitis C virus infection and three adverse maternal outcomes in the United States.PloS one · 2023Article
- Evaluation of machine learning algorithms for predicting direct-acting antiviral treatment failure among patients with chronic hepatitis C infection.Scientific reports · 2022Article
- Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7-year national inpatient sample study.Hepatology communications · 2022Article
- Effects of prenatal opioid and alcohol exposures on immune and serotonin factors in human placenta.Experimental neurology · 2022Article
- Article
- Effectiveness of interventions for prevention of common infections in people who use opioids: a protocol for a systematic review of systematic reviews.Systematic reviews · 2021Article
- Nucleic Acid Testing for Diagnosis of Perinatally Acquired Hepatitis C Virus Infection in Early Infancy.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021Article
- Association of Individual and Community Factors With Hepatitis C Infections Among Pregnant People and Newborns.JAMA health forum · 2021Article
- Women in the 2019 hepatitis C cascade of care: findings from the British Columbia Hepatitis Testers cohort study.BMC women's health · 2021Article
- Development of an unannounced standardized patient protocol to evaluate opioid use disorder treatment in pregnancy for American Indian and rural communities.Addiction science & clinical practice · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis C virus (HCV) is transmitted primarily through parenteral exposures to infectious blood or body fluids that contain blood (e.g., via injection drug use, needle stick injuries) (1). In the last 10 years, increases in HCV infection in the general U.S. population (1) and among pregnant women (2) are attributed to a surge in injection drug use associated with the opioid crisis. Opioid use disorders among pregnant women have increased (3), and approximately 68% of pregnant women with HCV infection have opioid use disorder (4). National trends in HCV infection among pregnant women by opioid use disorder status have not been reported to date. CDC analyzed hospital discharge data from the 2000-2015 Healthcare Cost and Utilization Project (HCUP) to determine whether HCV infection trends differ by opioid use disorder status at delivery. During this period, the national rate of HCV infection among women giving birth increased >400%, from 0.8 to 4.1 per 1,000 deliveries. Among women with opioid use disorder, rates of HCV infection increased 148%, from 87.4 to 216.9 per 1,000 deliveries, and among those without opioid use disorder, rates increased 271%, although the rates in this group were much lower, increasing from 0.7 to 2.6 per 1,000 deliveries. These findings align with prior ecological data linking hepatitis C increases with the opioid crisis (2). Treatment of opioid use disorder should include screening and referral for related conditions such as HCV infection.
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