Evidence map›Paper›PMID 31581067›Full record

ArticleiScience2019

Longitudinal In Vivo Assessment of Host-Microbe Interactions in a Murine Model of Pulmonary Aspergillosis.

Shweta Saini, Jennifer Poelmans, Hannelie Korf, James L Dooley, Sayuan Liang, Bella B Manshian, Rein Verbeke, Stefaan J Soenen, Greetje Vande Velde, Ine Lentacker and 5 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Shweta SainiBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Jennifer PoelmansBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Hannelie KorfLaboratory of Hepatology, CHROMETA Department, KU Leuven, Leuven, Belgium.
James L DooleyLaboratory of Genetics of Autoimmunity (VIB-KU Leuven Center for Brain & Disease Research), Leuven, Belgium.
Sayuan LiangBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium; Philips Research China, Shanghai, China.
Bella B ManshianBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Rein VerbekeGhent Research Group on Nanomedicines, Ghent University, Belgium.
Stefaan J SoenenBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Greetje Vande VeldeBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium.
Ine LentackerGhent Research Group on Nanomedicines, Ghent University, Belgium.
Katrien LagrouClinical Bacteriology and Mycology, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
Adrian ListonLaboratory of Genetics of Autoimmunity (VIB-KU Leuven Center for Brain & Disease Research), Leuven, Belgium.
Conny GysemansClinical and Experimental Endocrinology, KU Leuven, Leuven, Belgium.
Stefaan C De SmedtGhent Research Group on Nanomedicines, Ghent University, Belgium.
Uwe HimmelreichBiomedical MRI/Molecular Small Animal Imaging Center (MoSAIC), KU Leuven, Leuven, Belgium. Electronic address: uwe.himmelreich@kuleuven.be.
KU Leuven · BEGhent University · BEVIB-KU Leuven Center for Brain & Disease Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The fungus Aspergillus fumigatus is ubiquitous in nature and the most common cause of invasive pulmonary aspergillosis (IPA) in patients with a compromised immune system. The development of IPA in patients under immunosuppressive treatment or in patients with primary immunodeficiency demonstrates the importance of the host immune response in controlling aspergillosis. However, study of the host-microbe interaction has been hampered by the lack of tools for their non-invasive assessment. We developed a methodology to study the response of the host's immune system against IPA longitudinally in vivo by using fluorine-19 magnetic resonance imaging (

Indexed as

Infection Control in Health TechnologyMedical ImagingMycology

Identifiers

PMID31581067
PMCPMC6817634
OpenAlexW2973529716

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.