ArticleAnnals of Saudi medicine
Predictors of early recipient mortality after living donor liver transplantation in a tertiary care center in Egypt.
Article in Annals of Saudi medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- The Survival Rate of Living-Donor Liver Transplantation Between Same-Sex and Opposite-Sex Recipients.Diagnostics (Basel, Switzerland) · 2025Article
- Effects of immediate extubation in the operating room on long-term outcomes in living donor liver transplantation: a retrospective cohort study.Anesthesia and pain medicine · 2025Article
- In-hospital mortality of liver transplantation and risk factors: a single-center experience.Annals of translational medicine · 2021Article
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Authors and funding
9 authors.
Funding
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Abstract
backgroundLiving donor liver transplantation (LDLT) has evolved into a widely accepted therapeutic option. Many different risk factors may affect early mortality after LDLT.
objectivesAnalyze risk factors that can affect early (<6 months) mortality of patients after LDLT in a single center.
designRetrospective chart review of patients who underwent LDLT.
settingUniversity hospital. PATIENTS AND
methodsAdult cirrhotic patients who underwent LDLT were classified by early (first 6 months) or late mortality. A full pre, intra- and post-operative evaluation had been done on all patients including a full history, examination and investigations to identify risk factors that might affect mortality post-LDLT.
main outcome measuresDetermination of pre-, intra- or postoperative factors that might affect recipient mortality post-LDLT. SAMPLE SIZE: 123.
resultsPre-operative factors that increased early mortality in a univariate analysis were higher model for end-stage liver disease (MELD) scores, lower graft-recipient weigh ratio (GRWR), older donor age, and recurrent spontaneous bacterial peritonitis. Intraoperative factors included more transfusion units of blood, plasma, platelets and cryoprecipitate, a longer time for cold and warm ischemia, and a longer anhepatic phase among others. Postoperative factors included a longer ICU or hospital stay and abnormal postoperative laboratory data. In the final logistic regression model, the most significant factors were pre-operative GRWR, length of hospital stay, units of intraoperative blood transfusion, postoperative alanine aminotransferase, postoperative total leukocyte count, and MELD score.
conclusionLDLT outcomes might be improved by attempting to resolve clinical factors that have been identified as contributors to early post-LDLT mortality. LIMITATIONS: More risk factors, such as those relevant to patient portal vein hemodynamics, should be included in an analysis of predictors of early mortality. CONFLICT OF INTEREST: None.
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