ArticleActa bio-medica : Atenei Parmensis2019
Evaluation of the antimicrobial activity of novel composite plastics containing two silver (I) additives, acyl pyrazolonate and acyl pyrazolone.
Article in Acta bio-medica : Atenei Parmensis, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Antimicrobial Properties of Ti- and Zr-Based Nanotextured Thin Film Metallic Glasses AgainstBiomolecules · 2026Article
- Assessing non-porous antimicrobial surfaces against bacteria, phages and fungi: a comparative study under varied normative conditions using glass as a benchmark for microbial persistence.BMC microbiology · 2026Article
- Active Packaging Based on a PET/PP Food-Grade Film Coated with Pullulan and Clove Essential Oil: Physicochemical and Antimicrobial Properties.Molecules (Basel, Switzerland) · 2025Article
- Antimicrobial coatings effectively inactivate multidrug-resistantFrontiers in microbiology · 2025Article
- Silver phosphate-modified carbonate apatite honeycomb scaffolds for anti-infective and pigmentation-free bone tissue engineering.Materials today. Bio · 2024Article
- Addition of Silver Nanoparticles to Composite Edible Films and Coatings to Enhance Their Antimicrobial Activity and Application to Cherry Preservation.Foods (Basel, Switzerland) · 2023Article
- Antimicrobial Functionalization of Prolamine-Silica Hybrid Coatings with Fumaric Acid for Food Packaging Materials and Their Biocompatibility.Antibiotics (Basel, Switzerland) · 2022Article
- Antimicrobial Photodynamic Coatings Reduce the Microbial Burden on Environmental Surfaces in Public Transportation-A Field Study in Buses.International journal of environmental research and public health · 2022Article
- Novel Antibacterial Modification of Polycarbonate for Increment Prototyping in Medicine.Materials (Basel, Switzerland) · 2021Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPublic health systems today face the dual challenges of controlling infections and curbing the increase in antimicrobial resistance manifested in drug-resistant microorganisms in hospitals and elsewhere. In the last ten years, research has been conducted to develop new materials with antimicrobial properties to be used in medical devices, increasingly found to harbour critical nosocomial infections.
methodsTwo next-generation composites using the antimicrobial qualities of silver were tested against Escherichia coli, Staphylococcus aureus and Candida albicans with the purpose of evaluating their antimicrobial and antifungal activity. These tests applied the standardized method according to ISO-2216: Plastics-Measurement of Antibacterial Activity on Plastics Surfaces. Testing was carried out using polyethylene (PE) enriched with AgNO3 as a positive control and PE as a negative control.
resultsThe antimicrobial activity of the composites proved to be between medium (bacteriostatic) and very good (bactericidal). In particular, PE2 showed the highest scores against all microorganisms, with values ranging from good to very good. Instead, PE1 had lower scores, with a value of medium for Escherichia coli and slight for Candida albicans. Statistical analysis carried out with the t-test for unpaired data showed a statistically significant difference between the positive control and the other polymers (p< .0001).
conclusionsBased on our findings, we conclude that the test, conducted to ISO-2216 standards, could be extended to include fungal strains and that the new composites could be used to produce antimicrobial surfaces for medical devices, for example, intubation tubes, urinary catheters, vascular prostheses, and mechanical heart valves. This would reduce the risk of microbial contamination and biofilm formation, ensuring better health outcomes for patients treated with these devices. Further testing should be done to evaluate potential future applications of these composites and the possibility of adding fungal strains to the IS0-2216 standard.
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