Evidence map›Paper›PMID 31580141›Full record

ArticlePsychological methods2019

Challenges and suggestions for defining replication "success" when effects may be heterogeneous: Comment on Hedges and Schauer (2019).

Maya B Mathur, Tyler J VanderWeele

Abstract readComment
In one paragraph

Article in Psychological methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Toward Open and Reproducible Epidemiology.American journal of epidemiology · 2023
    Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Maya B MathurDepartment of Epidemiology, Harvard T. H. Chan School of Public Health.
Tyler J VanderWeeleDepartment of Epidemiology, Harvard T. H. Chan School of Public Health.

Funding

Theory and methods for mediation and interactionR01CA222147 · NCI · HARVARD SCHOOL OF PUBLIC HEALTH · PI TCHETGEN TCHETGEN, ERIC JOEL, VANDERWEELE, TYLER · 2018 to 2022
$2.1M
NCI NIH HHS R01 CA222147NIH HHS
6 · The paper itself

Abstract

Psychological scientists are now trying to replicate published research from scratch to confirm the findings. In an increasingly widespread replication study design, each of several collaborating sites (such as universities) independently tries to replicate an original study, and the results are synthesized across sites. Hedges and Schauer (2019) proposed statistical analyses for these replication projects; their analyses focus on assessing the extent to which results differ across the replication sites, by testing for heterogeneity among a set of replication studies, while excluding the original study. We agree with their premises regarding the limitations of existing analysis methods and regarding the importance of accounting for heterogeneity among the replications. This objective may be interesting in its own right. However, we argue that by focusing only on whether the replication studies have similar effect sizes to one another, these analyses are not particularly appropriate for assessing whether the replications in fact support the scientific effect under investigation or for assessing the power of multisite replication projects. We reanalyze Hedges and Schauer's (2019) example dataset using alternative metrics of replication success that directly address these objectives. We reach a more optimistic conclusion regarding replication success than they did, illustrating that the alternative metrics can lead to quite different conclusions from those of Hedges and Schauer (2019). (PsycINFO Database Record (c) 2019 APA, all rights reserved).

Indexed as

Research DesignReproducibility of Results

Identifiers

PMID31580141
PMCPMC6779319

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.