Evidence map›Paper›PMID 31580010›Full record

ArticleMicrobiologyOpen2020

Antimicrobial activity and chemical composition of white birch (Betula papyrifera Marshall) bark extracts.

Dorian Blondeau, Annabelle St-Pierre, Nathalie Bourdeau, Julien Bley, André Lajeunesse, Isabel Desgagné-Penix

Abstract read
In one paragraph

Article in MicrobiologyOpen, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. From traditional remedy toFrontiers in pharmacology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Authentication and Market Survey of Sweet Birch (Plants (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. RNA-Seq de Novo Assembly and Differential Transcriptome Analysis of Chaga (International journal of molecular sciences · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dorian BlondeauDepartment of Chemistry, Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, QC, Canada.
Annabelle St-PierreDepartment of Chemistry, Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, QC, Canada.
Nathalie BourdeauInnofibre, Cégep of Trois-Rivières, Trois-Rivières, QC, Canada.
Julien BleyInnofibre, Cégep of Trois-Rivières, Trois-Rivières, QC, Canada.
André LajeunesseDepartment of Chemistry, Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, QC, Canada.
Isabel Desgagné-PenixDepartment of Chemistry, Biochemistry and Physics, University of Québec at Trois-Rivières, Trois-Rivières, QC, Canada.ORCID 0000-0002-4355-5503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracts from white birch have been reported to possess antimicrobial properties, but no study has linked the chemical composition of bark extract with antimicrobial activity. This study aimed to identify white birch (Betula papyrifera Marshall) bark extracts with antimicrobial activity and elucidate its composition. In order to obtain the highest extraction yield, bark residues >3 mm were retained for extraction. A total of 10 extraction solvents were used to determine the extraction yield of each of them. Methanol and ethanol solvents extracted a greater proportion of molecules. When tested on eight microorganism species, the water extract proved to have the best antimicrobial potential followed by the methanol extract. The water extract inhibited all microorganisms at low concentration with minimal inhibitory concentration between 0.83 and 1.67 mg/ml. Using ultraperformance liquid chromatography coupled to a time-of-flight quadrupole mass spectrometer, several molecules that have already been studied for their antimicrobial properties were identified in water and methanol extracts. Catechol was identified as one of the dominant components in white birch bark water extract, and its antimicrobial activity has already been demonstrated, suggesting that catechol could be one of the main components contributing to the antimicrobial activity of this extract. Thus, extractives from forestry wastes have potential for new applications to valorize these residues.

Indexed as

Anti-Infective AgentsBacteriaBetulaCatecholsFungiMicrobial Sensitivity TestsPlant BarkPlant ExtractsAnti-Infective AgentscatecholCatecholsPlant Extractsantimicrobial activitybark extractsBetula papyrifera Marshallmass spectrometrywhite birch

Identifiers

PMID31580010
PMCPMC6957409

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.