ArticleScience advances2019
Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations.
Article in Science advances, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
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Who cites it
80 citing papers in PubMed, 156 citations in OpenAlex.
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- Comparative Genomic Screening Identifies Developmental Constraint Loci Underscoring the Phenotypic Evolution of Syngnathids.Integrative zoology · 2026Article
- Deep Dive into Evolution: How Cetaceans Adapt Their Anticoagulant Genes for Underwater Survival.Journal of molecular evolution · 2026Article
- The genetic foundations of convergent traits.Nature reviews. Genetics · 2026Review
- Molecular Evidence for the Parallel Evolution of Anosmia in Multiple Odontoceti (Toothed Whales) Clades.Genes · 2026Article
- The genomic basis of independent marine transitions in turtles: convergent episodic adaptation and demographic shifts.Molecular biology and evolution · 2026Article
- Hyper-specialized primates possess a reduced suite of xenobiotic-metabolizing cytochrome P450 genes.Molecular phylogenetics and evolution · 2026Article
- Rabies and Pinnipeds Reviewed: Premonitions, Perturbations, and Projections?Veterinary sciences · 2026Review
- Pseudogenes document protracted parallel regression of oral anatomy in myrmecophagous mammals.Molecular biology and evolution · 2026Article
- Parallel Erosion of a Testis-Specific Na+/K+ ATPase in Three Mammalian Lineages Sheds Light into the Evolution of Spermatozoa Energetics.Genome biology and evolution · 2026Article
- Molecular divergence ofZoological research · 2026Article
- Pygmy sperm whale multi-omics data reveal hypoxia adaptations in deep-diving cetaceans.BMC biology · 2025Article
- Insights from the Evolution of Coagulation: A New Perspective on Anti-Inflammatory Strategies in the ICU-Focus on the Contact Activation System.Biomedicines · 2025Review
- Phylogenomic Approaches to Study Adaptive Evolution in Mammals: From Aging to Aquatic Lifestyles.Annual review of genetics · 2025Review
- Cetacean loss of the master adipose tissue regulator βNature communications · 2025Article
- Patterns and Processes of Genomic Evolution Inferred From the Ten Smallest Vertebrate Genomes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Illuminating the mystery of thylacine extinction: a role for relaxed selection and gene loss.Proceedings. Biological sciences · 2025Article
- Adaptive evolution ofZoological research · 2025Article
- Deciphering genetic adaptations of Old World camels through comparative genomic analyses across all camelid species.iScience · 2025Article
- Gene Loss DB: a curated database for gene loss in mammals-the cetacean collection.Database : the journal of biological databases and curation · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The transition from land to water in whales and dolphins (cetaceans) was accompanied by remarkable adaptations. To reveal genomic changes that occurred during this transition, we screened for protein-coding genes that were inactivated in the ancestral cetacean lineage. We found 85 gene losses. Some of these were likely beneficial for cetaceans, for example, by reducing the risk of thrombus formation during diving (
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