ArticleCureus2019
The Prevalence and Determinants of Vitamin D Inadequacy among U.S. Older Adults: National Health and Nutrition Examination Survey 2007-2014.
Article in Cureus, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05795946 (Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.), which is not on this map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Effect of smoking on vitamin D status in the adults of Henan, China: the role of HDL-C and LDL-C.Scientific reports · 2026Article
- Vitamin D Deficiency, Obesity, and Metabolic Parameters in Chilean Older Adults.Journal of personalized medicine · 2026Article
- The Sunshine Paradox: Unraveling Risk Factors for Low Vitamin D Status Among Non-Pregnant Women in Lebanon.Nutrients · 2025Article
- Serum Vitamin D Status in Older Adults: A Cohort Study.Iranian journal of medical sciences · 2023Article
- The impact of vitamin and mineral supplements usage prior to COVID-19 infection on disease severity and hospitalization.Bosnian journal of basic medical sciences · 2022Article
- Influences of Vitamin D and Iron Status on Skeletal Muscle Health: A Narrative Review.Nutrients · 2022Review
- Vitamin D attenuates COVID-19 complications via modulation of proinflammatory cytokines, antiviral proteins, and autophagy.Expert review of anti-infective therapy · 2022Review
- Article
- Influence of climate factors on pediatric alopecia areata flares in Philadelphia, Pennsylvania.Scientific reports · 2021Article
- Vitamin D deficiency in African Americans is associated with a high risk of severe disease and mortality by SARS-CoV-2.Journal of human hypertension · 2021Article
- Vitamin D status and its longitudinal association with changes in patterns of sleep among middle-aged urban adults.Journal of affective disorders · 2021Article
- One health disparities and COVID-19.Evolution, medicine, and public health · 2021Review
- Shining Light on the COVID-19 Pandemic: A Vitamin D Receptor Checkpoint in Defense of Unregulated Wound Healing.Cell metabolism · 2020Article
- Dietary Interventions to Prevent or Delay Alzheimer's Disease: What the Evidence Shows.Current nutrition reports · 2020Review
- Vitamin D Synthesis Following a Single Bout of Sun Exposure in Older and Younger Men and Women.Nutrients · 2020Article
- Could Vitamin D influence risk for Periodontal Disease - to "D" or not to "D"?Current oral health reports · 2020Article
- The Association between Body Mass Index and Vitamin D Supplement Use among Adults in the United States.Cureus · 2019Article
- Differences in RAAS/vitamin D linked to genetics and socioeconomic factors could explain the higher mortality rate in African Americans with COVID-19.Therapeutic advances in cardiovascular diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Older adults (i.e., adults aged ≥ 60 years) are at higher risk of vitamin D deficiency compared to younger adults as a result of inadequate dietary vitamin D intake and limited exposure to sunlight. Thus, the present study aimed to describe the prevalence of vitamin deficiency and inadequacy among U.S. adults aged ≥ 60 years and the effect of vitamin D supplementation on 25, hydroxyvitamin D (25(OH)D) and its metabolites concentrations. Methods The present analysis was based on data from 6,261 participants in the National Health and Nutrition Examination Survey cycles 2007/2008 through 2013/2014. The prevalence of vitamin D deficiency and inadequacy was described according to demographic, behavioral, and health characteristics. Vitamin D deficiency was defined as 25(OH)D < 30 nmol/L; and vitamin D inadequacy was defined as < 50 nmol/L. Logistic regression models were assembled to examine the independent association of participants characteristics and the odds of having 25(OH)D inadequacy. Similarly, general linear models were used to assess the effect of vitamin D supplementation doses on 25(OH)D and its metabolites concentrations. Results The prevalence of 25(OH)D deficiency and inadequacy was 4.0% (standard error (SE), 0.4) and 17.4% (SE, 0.8), respectively. In general, the prevalence of 25(OH)D deficiency and inadequacy increased significantly among participants examined during the fall and winter months, women, non-Hispanic black patients, obese subjects, smokers, those physically inactive, and older adults with a daily vitamin D intake < 400 IU. After adjustment for potential confounders, subjects examined during the fall and winter months, females, non-Hispanic blacks, obesity, having a sedentary lifestyle, smokers, and a total vitamin D intake < 400 IU/day were variables significantly associated with increased odds of having vitamin D inadequacy. Notably, vitamin D supplement doses between 400 and 800 IU or > 800 IU/day were significantly correlated with higher 25(OH)D
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.