Evidence map›Paper›PMID 31579488›Full record

ArticleEuropean journal of translational myology2019

Stiffness and echogenicity: Development of a stiffness-echogenicity matrix for clinical problem solving.

Antonio Stecco, Carmelo Pirri, Raffaele De Caro, Preeti Raghavan

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in European journal of translational myology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06898242 (Early Myofascial Manual Treatment in Subjects With Spasticity Following Acquired Brain Injury), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06898242 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Early Myofascial Manual Treatment in Subjects With Spasticity Following Acquired Brain Injury

TypeinterventionalSponsorFondazione Policlinico Universitario Agostino Gemelli IRCCSRan2025 to 2026Enrolled24ConditionsBrain Injury, Brain Injury, Vascular, Brain Injuries, TraumaticArmsManual myofascial treatment direct to upper and lower limb, Rehabilitative treatment following rehabilitation project
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Hyaluronan homeostasis and its role in pain and muscle stiffness.PM & R : the journal of injury, function, and rehabilitation · 2022
    Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Antonio SteccoRUSK Rehabilitation, New York University School of Medicine, New York, USA.
Carmelo PirriPhysical and Rehabilitation Medicine, Department of Clinical Sciences and Translational Medicine, "Tor Vergata" University, Rome, Italy.
Raffaele De CaroDepartment of Neuroscience, Institute of Human Anatomy, University of Padova, Padova, Italy.
Preeti RaghavanDepartments of Physical Medicine and Rehabilitation and Neurology, Johns Hopkins University School of Medicine, Baltimore, USA.
Johns Hopkins Medicine · USNeuroscience Institute · ITRusk Rehabilitation · USUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The assessment of soft tissue stiffness is important to evaluate many neuromusculoskeletal conditions. Several tools have been proposed for the assessment of stiffness, but ultrasonography appears to be most practical. The reflection of ultrasound waves as it travels through tissue enables assessment of tissue echogenicity, which is influenced by the characteristics of the sound wave as well as the characteristics of the tissue through which it passes, such as the amount of fat and fibrous tissue. However, tissue stiffness is not directly proportional to its echogenicity. Hence evaluation of echogenicity, as a stand-alone technique, is inadequate to describe its mechanical properties. The aim of this manuscript is to present a method of combining echogenicity evaluation by ultrasound and stiffness evaluation by palpation to better describe the mechanical properties of muscle using a stiffness-echogenicity matrix.

Indexed as

echogenicityelastographystiffnessultrasound

Identifiers

PMID31579488
PMCPMC6767937
OpenAlexW2972745122

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.