Evidence map›Paper›PMID 31579423›Full record

ArticleOncology letters2019

Multiple primary malignant neoplasms: A case report and literature review.

Linwei Zhang, Lingxin Feng, Hui Cong, Zhuang Yu, Haocheng Wang, Ya Dong, Jing Wang

Abstract read
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Linwei ZhangDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Lingxin FengDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Hui CongDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Zhuang YuDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Haocheng WangDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Ya DongDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.
Jing WangDepartment of Oncology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Until recently, few cases of three or more malignant tumors in one patient have been reported. Owing to the high incidence rate of these tumors, the improvement in cancer diagnosis and treatment, and the extension of patient survival time, the incidence of reported multiple primary malignant neoplasms has gradually increased. The present study reported the case of a 57-year-old man with non-small cell lung cancer combined with B-Raf proto-oncogene serine/threonine kinase V600E mutation, gastrointestinal stromal tumors and lumbar vertebral malignant mucinous sarcoma. The pathogenesis, diagnosis and treatment of these three malignancies are discussed and previous studies are also reviewed. The aim of the study was to analyze the genetic mutations associated with multiple primary malignant tumors and to discuss whether those mutations with unknown functional significance could be used as therapeutic indicators. This case report will serve as a reference for future treatment of such patients.

Indexed as

BRAF V600E mutationdabrafenibgastrointestinal stromal tumorimatinibmalignant fibromyxoid sarcomamultiple primary malignant neoplasmsnon-small cell lung cancerPD-L1trametinib

Identifiers

PMID31579423
PMCPMC6757307

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.