ReviewCurrent urology2019
Hyperviscous Semen Causes Poor Sperm Quality and Male Infertility through Induction of Oxidative Stress.
Review in Current urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 29 citations in OpenAlex.
- Expression and correlation of male reproductive hormone levels with abnormal semen liquefaction time.Annals of medicine · 2025Article
- Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025Review
- Correlation analysis between semen routine parameters and sperm DNA fragmentation index in patients with semen non-liquefaction: A retrospective study.Open life sciences · 2025Article
- The Role of Selected Elements in Oxidative Stress Protection: Key to Healthy Fertility and Reproduction.International journal of molecular sciences · 2024Review
- Testicular protective effects of hesperidin against chemical and biological toxicants.Toxicology research · 2024Review
- Article
- The Palliative and Antioxidant Effects of Hesperidin against Lead-Acetate-Induced Testicular Injury in Male Wistar Rats.Biomedicines · 2023Article
- Levels of DNA, Protein, Lipid Oxidation and Apoptosis Biomarkers in Semen of Men with Hyperviscous Semen: A Cross-Sectional Study.International journal of fertility & sterility · 2023Article
- Semen rheology and its relation to male infertility.Interface focus · 2022Review
- Epigenetic Modifications, A New Approach to Male Infertility Etiology: A Review.International journal of fertility & sterility · 2022Review
- Irisin alleviates obesity-related spermatogenesis dysfunction via the regulation of the AMPKα signalling pathway.Reproductive biology and endocrinology : RB&E · 2021Article
- The Relationship between Seminal Fluid Hyperviscosity and Oxidative Stress: A Systematic Review.Antioxidants (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsSemen hyperviscosity (SHV) is one of the significant factors involved in poor semen quality and male infertility. It also leads major problems during assisted reproduction techniques and
methodsA PubMed/Medline and EM-BASE search was performed using keywords: "hyperviscosity semen", "oxidative stress", and "male infertility".
conclusionOS induced by reactive oxygen species can be considered as a major mechanism in patients with hyperviscosity semen that is associated with DNA fragmentation, lipid peroxidation and sperm membrane disintegrity, apoptosis, depletion of antioxidants, and subsequently poor sperm quality and male infertility. Therefore, antioxidant therapy may improve main pathological effects of hyperviscosity semen, especially oxidative damages and inflammation, on sperm quality and function. Further, randomized controlled studies are necessary to confirm these results and make a comparison between effects of various antioxidants such as N-acethyl-cysteine and Curcumin on fertility problem in patients with hyperviscous semen.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.