Evidence map›Paper›PMID 31579200›Full record

ArticleCurrent urology2019

Renal Cell Carcinoma Follow-Up - Is it Time to Abandon Ultrasound?

Mark Quinlan, Gavin Wei, Niall Davis, Cedric Poyet, Marlon Perera, Damien Bolton, Nathan Lawrentschuk

Open access · diamondAbstract read
In one paragraph

Article in Current urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mark QuinlanUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Gavin WeiUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Niall DavisUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Cedric PoyetUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Marlon PereraUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Damien BoltonUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Nathan LawrentschukUniversity of Melbourne, Department of Surgery, Urology Unit, Austin Hospital.
Austin Hospital · AUProstate Cancer Foundation of Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe wished to compare the efficacy of ultrasound versus intravenous contrast-enhanced computed tomography (CT) for detecting recurrent renal cell carcinoma (RCC) by identifying patients presenting with such tumor burden and to evaluate the utility of these imaging modalities in these circumstances.

methodsPatients who developed local and/or distant recurrences following surgical intervention for RCC were identified. The imaging regimen utilized during post-operative surveillance was analyzed to determine whether recurrent disease was identifiable on ultrasound or CT or both.

resultsOf the 22 patients with recurrent RCC, 16 had previously undergone radical nephrectomy and 6 had undergone partial nephrectomy. Median duration to RCC recurrence was 28.5 months (range 2-66 months). Fourteen patients (64%) underwent ultrasound during their follow-up surveillance protocol and 1 case of disease recurrence was detected by ultrasound before subsequent con-frmation with CT. All 22 patients underwent CT as a routine component of their follow-up surveillance protocol and all recurrences were detected by this modality. Six patients had recurrence in their ipsilateral kidney after partial nephrec-tomy - five had undergone ultrasound in their surveillance protocol and this modality failed to detect a recurrence in four of these patients.

conclusionUltrasound is inferior to CT for detecting recurrent RCC. CT should be recognized as the standard diagnostic modality during post-operative surveillance, in contradiction to what is recommended in many guidelines.

Indexed as

Computed tomographyDetectionGuidelinesRecurrenceRenal cell cancerUltrasound

Identifiers

PMID31579200
PMCPMC6771069
OpenAlexW2972903305

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.