Trial reportJournal of medical Internet research2019
Diminishing Effects After Recurrent Use of Self-Guided Internet-Based Interventions in Depression: Randomized Controlled Trial.
Trial report in Journal of medical Internet research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03795480 (A Randomized-controlled Trial), which is not on this map. Cited by 13 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized-controlled Trial (RCT) on the Efficacy of a New Online Intervention for Depression: MOOD
Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Acceptability of Digital Mental Health Interventions for Depression and Anxiety: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Race, Ethnicity, and Other Cultural Background Factors in Trials of Internet-Based Cognitive Behavioral Therapy for Depression: Systematic Review.Journal of medical Internet research · 2024Pooled it
- Characteristics of Mobile Health Platforms for Depression and Anxiety: Content Analysis Through a Systematic Review of the Literature and Systematic Search of Two App Stores.Journal of medical Internet research · 2022Pooled it
- Efficacy of web-based self-management interventions for depressive symptoms: a meta-analysis of randomized controlled trials.BMC psychiatry · 2021Pooled it
- Exploring the Role of Persuasive Design in Unguided Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Among Adults: Systematic Review, Meta-analysis, and Meta-regression.Journal of medical Internet research · 2021Pooled it
- A randomized controlled trial on a self-guided Internet-based intervention for gambling problems.Scientific reports · 2021Trial
- Results of the Optimune trial: A randomized controlled trial evaluating a novel Internet intervention for breast cancer survivors.PloS one · 2021Trial
- Mobile Behavioral Health Coaching as a Preventive Intervention for Occupational Public Health: Retrospective Longitudinal Study.JMIR formative research · 2023Article
- Personalization strategies in digital mental health interventions: a systematic review and conceptual framework for depressive symptoms.Frontiers in digital health · 2023Review
- Motive-Oriented, Personalized, Internet-Based Interventions for Depression: Nonclinical Experimental Study.JMIR formative research · 2022Article
- Satisfaction and Acceptability Ratings of a Web-Based Self-help Intervention for Depression: Retrospective Cross-sectional Study From a Resource-Limited Country.JMIR formative research · 2022Article
- Digital Health Interventions in Prevention, Relapse, and Therapy of Mild and Moderate Depression: Scoping Review.JMIR mental health · 2021Article
- Impact of COVID-19 Pandemic Burnout on Cardiovascular Risk in Healthcare Professionals Study Protocol: A Multicenter Exploratory Longitudinal Study.Frontiers in medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSelf-guided internet-based interventions have several advantages over guided interventions and are generally effective in treating psychiatric symptoms.
objectiveWe aimed to investigate whether the use of a new self-guided internet-based intervention (MOOD) would lead to a significant reduction in depressive symptoms compared with a care-as-usual (CAU) control group in a sample of individuals with depressive symptoms, most of whom had already used a different self-guided internet-based intervention in a previous trial.
methodsA total of 125 individuals were randomized to the intervention condition (MOOD) and received access to the intervention for a period of six weeks or a CAU group. After six weeks, all participants were invited to take part in the post assessment. The Beck Depression Inventory-II served as the primary outcome.
resultsBoth intention-to-treat as well as per-protocol analyses indicated that the depressive symptomatology decreased in both conditions but showed no advantage for those who had used MOOD. Subsequent moderation analyses suggested that those individuals who had less experience with psychotherapy benefitted to a greater extent compared with those with more experience.
conclusionsSelf-guided internet-based interventions are deemed a suitable first-step approach to the treatment of depression. However, our results indicate that they are more efficacious in those with less psychotherapy experience.
trial registrationClinicalTrials.gov NCT03795480; http://clinicaltrials.gov/ct2/show/NCT03795480.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.