Evidence map›Paper›PMID 31578802›Full record

ReviewJournal of cellular and molecular medicine2019

Insights into IL-29: Emerging role in inflammatory autoimmune diseases.

Jia-Min Wang, An-Fang Huang, Wang-Dong Xu, Lin-Chong Su

Abstract readReview
In one paragraph

Review in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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  8. Article
  9. A Potential New Link Between Inflammation and Vascular Calcification.Journal of the American Heart Association · 2023
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Insights into IL-29: Emerging role in inflammatory autoimmune diseases.Journal of cellular and molecular medicine · 2019
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jia-Min WangDepartment of Evidence-Based Medicine, School of Public Health, Southwest Medical University, Sichuan, China.
An-Fang HuangDepartment of Rheumatology and Immunology, Affiliated Hospital of Southwest Medical University, Sichuan, China.ORCID 0000-0002-3860-8383
Wang-Dong XuDepartment of Evidence-Based Medicine, School of Public Health, Southwest Medical University, Sichuan, China.
Lin-Chong SuDepartment of Rheumatology and Immunology, Minda Hospital of Hubei Minzu University, Enshi, China.ORCID 0000-0002-3545-5270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interleukin-29 (IL-29) is a newly discovered member of type III interferon. It mediates signal transduction via binding to its receptor complex and activates downstream signalling pathways, and therefore induces the generation of inflammatory components. Recent studies reported that expression of IL-29 is dysregulated in inflammatory autoimmune diseases, such as rheumatoid arthritis, systemic lupus erythematosus, osteoarthritis, Sjögren's syndrome, psoriasis and systemic sclerosis. Furthermore, functional analysis revealed that IL-29 may involve in the pathogenesis of the inflammatory autoimmune disorders. In this review, we will systematically review the current knowledge about IL-29. The information collected revealed the regulatory role of IL-29 and may give important implications for its potential in clinical treatment.

Indexed as

Adaptive ImmunityAutoimmune DiseasesCytokinesHumansImmunity, InnateInflammationInterferon LambdaInterferonsInterleukinsSignal TransductionToll-Like ReceptorsCytokinesInterferon Lambdainterferon-lambda, humanInterferonsInterleukinsToll-Like Receptorsautoimmunityinflammationinterleukin-29signalling

Identifiers

PMID31578802
PMCPMC6850914

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.