Evidence map›Paper›PMID 31578442›Full record

ArticleScientific reports2019

Comparative modulation of lncRNAs in wild-type and rag1-heterozygous mutant zebrafish exposed to immune challenge with spring viraemia of carp virus (SVCV).

Valentina Valenzuela-Muñoz, Patricia Pereiro, Margarita Álvarez-Rodríguez, Cristian Gallardo-Escárate, Antonio Figueras, Beatriz Novoa

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Valentina Valenzuela-MuñozLaboratory of Biotechnology and Aquatic Genomics, Interdisciplinary Center for Aquaculture Research (INCAR), University of Concepción, Concepción, Chile.
Patricia PereiroLaboratory of Biotechnology and Aquatic Genomics, Interdisciplinary Center for Aquaculture Research (INCAR), University of Concepción, Concepción, Chile.
Margarita Álvarez-RodríguezInstituto de Investigaciones Marinas (IIM), CSIC, Vigo, Spain.
Cristian Gallardo-EscárateLaboratory of Biotechnology and Aquatic Genomics, Interdisciplinary Center for Aquaculture Research (INCAR), University of Concepción, Concepción, Chile. crisgallardo@udec.cl.
Antonio FiguerasInstituto de Investigaciones Marinas (IIM), CSIC, Vigo, Spain.
Beatriz NovoaInstituto de Investigaciones Marinas (IIM), CSIC, Vigo, Spain. beatriznovoa@iim.csic.es.
Instituto de Investigacións Mariñas · ESUniversity of Concepción · CLInterdisciplinary Center for Aquaculture Research · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the modulation of immune-related genes after viral infection has been widely described in vertebrates, the potential implications of non-coding RNAs (ncRNAs), especially long non-coding RNAs (lncRNAs), in immunity are still a nascent research field. The model species zebrafish could serve as a useful organism for studying the functionality of lncRNAs due to the numerous advantages of this teleost, including the existence of numerous mutant lines. In this work, we conducted a whole-transcriptome analysis of wild-type (WT) and heterozygous rag1 mutant (rag1

Indexed as

TranscriptomeAnimalsHeterozygoteHomeodomain ProteinsKidneyMutationRhabdoviridaeRNA, Long NoncodingViremiaZebrafishHomeodomain ProteinsRAG-1 proteinRNA, Long Noncoding

Identifiers

PMID31578442
PMCPMC6775065
OpenAlexW2978174796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.