Electroosmotic flow driven microfluidic device for bacteria isolation using magnetic microbeads.

Samuel Miller, Alison A Weiss, William R Heineman, Rupak K Banerjee

Open access · goldAbstract readComparative Study

In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

1.1field-weighted citation impact, top 24% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 24 citations in OpenAlex.

Microfluidic devices for studying bacterial taxis, drug testing and biofilm formation.Microbial biotechnology · 2022
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Samuel MillerDepartment of Mechanical and Materials Engineering, University of Cincinnati, 598 Rhodes Hall, University of Cincinnati, Cincinnati, OH, 45221, USA.

Alison A WeissDepartment of Molecular Genetics, Biochemistry & Microbiology, University of Cincinnati, 2254 Medical Sciences Building, 231 Albert Sabin Way, Cincinnati, OH, 45267, USA.ORCID http://orcid.org/0000-0002-4726-8376

William R HeinemanDepartment of Chemistry, University of Cincinnati, 120 Crosley Tower, PO Box 210172, Cincinnati, OH, 45221, USA.

Rupak K BanerjeeDepartment of Mechanical and Materials Engineering, University of Cincinnati, 593 Rhodes Hall, ML 0072, University of Cincinnati, Cincinnati, OH, 45221, USA. rupak.banerjee@uc.edu.

University of Cincinnati · USSabin Vaccine Institute · US

Funding

University of Cincinnati Education and Research CenterT42OH008432 · OH · UNIVERSITY OF CINCINNATI · PI DAVIS, KERMIT G. · 2005 to 2025

$32.7M

ACL HHS T42OH008432NIOSH CDC HHS T42 OH008432

6 · The paper itself

Abstract

The presence of bacterial pathogens in water can lead to severe complications such as infection and food poisoning. This research proposes a point-of-care electroosmotic flow driven microfluidic device for rapid isolation and detection of E. coli in buffered solution (phosphate buffered saline solution). Fluorescent E. coli bound to magnetic microbeads were driven through the microfluidic device using both constant forward flow and periodic flow switching at concentrations ranging from 2 × 10

Indexed as

ElectroosmosisLab-On-A-Chip DevicesMicrospheresBacteriological TechniquesCalibrationEquipment DesignEscherichia coliFluoresceinsFluorescent DyesFluorometrySulfonic Acidsalexa fluor 488FluoresceinsFluorescent DyesSulfonic Acids

Identifiers

PMID31578397

DOI10.1038/s41598-019-50713-z

PMCPMC6775156

OpenAlexW2978505367

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.