Evidence map›Paper›PMID 31578345›Full record

ArticleScientific reports2019

Sleep stage classification from heart-rate variability using long short-term memory neural networks.

Mustafa Radha, Pedro Fonseca, Arnaud Moreau, Marco Ross, Andreas Cerny, Peter Anderer, Xi Long, Ronald M Aarts

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. A skin-interfaced wireless wearable device and data analytics approach for sleep-stage and disorder detection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mustafa RadhaRoyal Philips, Research, High Tech Campus 34, 5656 AE, Eindhoven, The Netherlands. mustafa.radha@philips.com.ORCID http://orcid.org/0000-0003-0969-4013
Pedro FonsecaRoyal Philips, Research, High Tech Campus 34, 5656 AE, Eindhoven, The Netherlands.ORCID http://orcid.org/0000-0003-2932-6402
Arnaud MoreauPhilips Austria GmbH, Kranichberggasse 4, 1120, Vienna, Austria.
Marco RossPhilips Austria GmbH, Kranichberggasse 4, 1120, Vienna, Austria.ORCID http://orcid.org/0000-0003-0603-5709
Andreas CernyPhilips Austria GmbH, Kranichberggasse 4, 1120, Vienna, Austria.
Peter AndererPhilips Austria GmbH, Kranichberggasse 4, 1120, Vienna, Austria.
Xi LongRoyal Philips, Research, High Tech Campus 34, 5656 AE, Eindhoven, The Netherlands.ORCID http://orcid.org/0000-0001-9505-1270
Ronald M AartsRoyal Philips, Research, High Tech Campus 34, 5656 AE, Eindhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Automated sleep stage classification using heart rate variability (HRV) may provide an ergonomic and low-cost alternative to gold standard polysomnography, creating possibilities for unobtrusive home-based sleep monitoring. Current methods however are limited in their ability to take into account long-term sleep architectural patterns. A long short-term memory (LSTM) network is proposed as a solution to model long-term cardiac sleep architecture information and validated on a comprehensive data set (292 participants, 584 nights, 541.214 annotated 30 s sleep segments) comprising a wide range of ages and pathological profiles, annotated according to the Rechtschaffen and Kales (R&K) annotation standard. It is shown that the model outperforms state-of-the-art approaches which were often limited to non-temporal or short-term recurrent classifiers. The model achieves a Cohen's k of 0.61 ± 0.15 and accuracy of 77.00 ± 8.90% across the entire database. Further analysis revealed that the performance for individuals aged 50 years and older may decline. These results demonstrate the merit of deep temporal modelling using a diverse data set and advance the state-of-the-art for HRV-based sleep stage classification. Further research is warranted into individuals over the age of 50 as performance tends to worsen in this sub-population.

Indexed as

Heart RateNeural Networks, ComputerAdultAgedFemaleHumansMaleMiddle AgedModels, NeurologicalSleep Stages

Identifiers

PMID31578345
PMCPMC6775145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.