Evidence map›Paper›PMID 31578269›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2019

RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells.

Nico Andreas, Maria Potthast, Anna-Lena Geiselhöringer, Garima Garg, Renske de Jong, Julia Riewaldt, Dennis Russkamp, Marc Riemann, Jean-Philippe Girard, Simon Blank and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. New insights into the Lck-NF-κB signaling pathway.Frontiers in cell and developmental biology · 2023
    Review
  7. Article
  8. NF-κB in control of regulatory T cell development, identity, and function.Journal of molecular medicine (Berlin, Germany) · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Nico AndreasResearch Group Immunology, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany.ORCID 0000-0002-4591-7037
Maria PotthastZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.ORCID 0000-0001-7933-9426
Anna-Lena GeiselhöringerZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Garima GargKlinikum Rechts der Isar, Neurologische Klinik, Technische Universität München, 81675 Munich, Germany.
Renske de JongZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Julia RiewaldtMolecular and Cellular Immunology/Immune Regulation, German Research Foundation - Center for Regenerative Therapies Dresden, Center for Molecular and Cellular Bioengeneering, Technical University Dresden, 01307 Dresden, Germany.
Dennis RusskampZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Marc RiemannResearch Group Immunology, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany.
Jean-Philippe GirardInstitut de Pharmacologie et de Biologie Structural, Université de Toulouse, CNRS, UPS, 31077 Toulouse, France.
Simon BlankZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Karsten KretschmerMolecular and Cellular Immunology/Immune Regulation, German Research Foundation - Center for Regenerative Therapies Dresden, Center for Molecular and Cellular Bioengeneering, Technical University Dresden, 01307 Dresden, Germany.
Carsten Schmidt-WeberZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany.
Thomas KornKlinikum Rechts der Isar, Neurologische Klinik, Technische Universität München, 81675 Munich, Germany.ORCID 0000-0002-3633-0955
Falk WeihResearch Group Immunology, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany.
Caspar OhnmachtZentrum Allergie und Umwelt, Technische Universität und Helmholtz Zentrum München, 85764 Neuherberg, Germany; caspar.ohnmacht@helmholtz-muenchen.de.
Helmholtz Zentrum München · DELeibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DECenter for Systems Biology Dresden · DETUM Klinikum · DECentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Foxp3

Indexed as

AnimalsAutoimmunityCells, CulturedDendritic CellsEncephalomyelitis, Autoimmune, ExperimentalForkhead Transcription FactorsGene Knockout TechniquesHomeostasisImmune ToleranceInflammationInterleukin-33MiceMice, Inbred C57BLMice, KnockoutNF-kappa B p52 SubunitT-Lymphocytes, RegulatoryForkhead Transcription FactorsFoxp3 protein, mouseIl33 protein, mouseInterleukin-33NF-kappa B p52 SubunitRelb protein, mouseTranscription Factor RelB

Identifiers

PMID31578269
PMCPMC6826119
OpenAlexW2977718548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.