Evidence map›Paper›PMID 31578246›Full record

ArticlemSphere2019

PacBio Amplicon Sequencing Method To Measure Pilin Antigenic Variation Frequencies of Neisseria gonorrhoeae.

Egon A Ozer, Lauren L Prister, Shaohui Yin, Billy H Ward, Stanimir Ivanov, H Steven Seifert

Abstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Restriction-modification systems are required forProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Restriction-modification systems are required forbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Egon A Ozer *Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-7131-3691
Lauren L Prister *Department of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-4053-2645
Shaohui YinDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Billy H WardDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana, USA.
Stanimir IvanovDepartment of Microbiology and Immunology, Louisiana State University Health Sciences Center-Shreveport, Shreveport, Louisiana, USA.ORCID 0000-0002-3294-7595
H Steven SeifertDepartment of Microbiology-Immunology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA h-seifert@northwestern.edu.ORCID 0000-0001-8651-0375

Funding

Mechanisms of Gonococcal Pilin Antigenic/Phase VariationR37AI033493 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Hank S. SEIFERT · 2003 to 2026
$10.1M
NIAID NIH HHS R37 AI033493
6 · The paper itself

Abstract

Gene diversification is a common mechanism pathogens use to alter surface structures to aid in immune avoidance.

Indexed as

Antigenic VariationFimbriae ProteinsGonorrheaHumansNeisseria gonorrhoeaeSequence Analysis, DNASoftwareU937 CellsFimbriae ProteinspilE protein, Neisseria gonorrhoeaeamplicon sequencingantigenic variationgene diversificationPacific Biosciences sequencing

Identifiers

PMID31578246
PMCPMC6796969

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.