ArticleCancer research2020
Recreational Physical Activity Is Associated with Reduced Breast Cancer Risk in Adult Women at High Risk for Breast Cancer: A Cohort Study of Women Selected for Familial and Genetic Risk.
Registry-linked trialOpen access · greenAbstract readComment
In one paragraph
Article in Cancer research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06405568 (Support for Physical Activity for Adults Registered in the Ontario Breast Screening Program), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Support for Physical Activity for Adults Registered in the Ontario Breast Screening Program: A Randomized Controlled Trial
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Modifiable risk factors in women at high risk of breast cancer: a systematic review.Breast cancer research : BCR · 2023Pooled it
- Physical Activity in Young BRCA Carriers and Reduced Risk of Breast Cancer.American journal of preventive medicine · 2022Pooled it
- Randomised controlled trial of breast cancer and multiple disease prevention weight loss programmes vs written advice amongst women attending a breast cancer family history clinic.British journal of cancer · 2023Trial
- Association Between Physical Activity, Sedentary Behavior and Breast Cancer Risk Among Moroccan Women: A Multicenter Case-Control Study.Epidemiologia (Basel, Switzerland) · 2026Article
- Health Behaviors and Cancer Diagnosis Among Individuals with Pathogenic Variants Associated with Hereditary Breast and Ovarian Cancer or Lynch Syndrome.Journal of personalized medicine · 2025Article
- Global, Regional, and National Burden of Breast Cancer Attributable to Low Physical Activity in Women of Reproductive Age: Historical Trends from 1990 to 2021 and Projections to 2035.Archives of Iranian medicine · 2025Article
- Exercise Interventions in Breast Cancer: Molecular Mechanisms, Physical Benefits, and Practical Recommendations.Medicina (Kaunas, Lithuania) · 2025Review
- Genetic and epigenetic alterations in night shift nurses with breast cancer: a narrative review.Cancer cell international · 2025Review
- Physical Activity during Adolescence and Early Adulthood and Breast Cancer Risk before Age 40 Years.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025Article
- Advancing environmental epidemiologic methods to confront the cancer burden.American journal of epidemiology · 2025Article
- Menopausal hormone therapy: assessing associations with breast and colorectal cancers by familial risk.JNCI cancer spectrum · 2025Article
- Early breast cancer in youngTherapeutic advances in medical oncology · 2025Review
- Article
- Pregnancy-Related Factors and Breast Cancer Risk for Women Across a Range of Familial Risk.JAMA network open · 2024Article
- Epidemiology and Risk Factors for Breast Cancer: 21st Century Advances, Gaps to Address through Interdisciplinary Science.Cold Spring Harbor perspectives in medicine · 2023Review
- Inflammatory cytokine-enriched microenvironment plays key roles in the development of breast cancers.Cancer science · 2023Review
- Review
- Evaluating the Acceptance and Usability of an App Promoting Weight Gain Prevention and Healthy Behaviors Among Young Women With a Family History of Breast Cancer: Protocol for an Observational Study.JMIR research protocols · 2022Article
- Molecular mechanisms of exercise contributing to tissue regeneration.Signal transduction and targeted therapy · 2022Review
- Health Behavior and Cancer Prevention among Adults with Li-Fraumeni Syndrome and Relatives in Germany-A Cohort Description.Current oncology (Toronto, Ont.) · 2022Article
Corrections and comments
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Authors and funding
25 authors at 11 institutions in 3 countries.
Rebecca D KehmDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.ORCID 0000-0002-6089-6799
Jeanine M GenkingerDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.
Robert J MacInnisCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Esther M JohnDepartment of Medicine and Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.ORCID 0000-0003-3259-8003
Kelly-Anne PhillipsCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia; Division of Cancer Medicine, Peter MacCallum Cancer Centre, Melbourne, Australia; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-0475-1771
Gillian S DiteCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-2448-2548
Roger L MilneCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.ORCID 0000-0001-5764-7268
Nur ZeinomarDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Yuyan LiaoDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
Julia A KnightLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Melissa C SoutheyPrecision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia; Department of Clinical Pathology, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-6313-9005
Wendy K ChungDepartment of Pediatrics and Medicine, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, New York; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York.
Graham G GilesCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia; Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.ORCID 0000-0003-4946-9099
Sue-Anne McLachlanDepartment of Medicine, St Vincent's Hospital, The University of Melbourne, Melbourne, Australia; Department of Medical Oncology, St Vincent's Hospital, Melbourne, Australia.
Kristen D WhitakerDepartment of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
Michael FriedlanderPrince of Wales Clinical School, University of New South Wales, Sydney, Australia; Department of Medical Oncology, Prince of Wales Hospital, Sydney, Australia.ORCID 0000-0003-3090-795X
Prue C WeidemanCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia.ORCID 0000-0002-3672-5201
Gord GlendonLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.
Stephanie NesciDepartment of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia.
kConFab InvestigatorsSir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Australia; The Research Department, The Peter MacCallum Cancer Centre, Melbourne, Australia.
Irene L AndrulisLunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada; Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.
Saundra S BuysDepartment of Medicine and Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah.
Mary B DalyDepartment of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
John L HopperCentre for Epidemiology and Biostatistics, The University of Melbourne, Melbourne, Australia.
Mary Beth TerryDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, New York. mt146@cumc.columbia.edu.
The University of Melbourne · AUColumbia University · USColumbia University Irving Medical Center · USFox Chase Cancer Center · USLunenfeld-Tanenbaum Research Institute · CAHuntsman Cancer Institute · USPeter MacCallum Cancer Centre · AUPrince of Wales Hospital · AUStanford Medicine · USSt Vincent's Hospital Melbourne · AUUniversity of Toronto · CA
Funding
Core-001U01CA164920 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Irene Andrulis, Sarah Violet Colonna · 2018 to 2026
$17.0MGenes, environment and breast cancer risk: The 15 year follow-up of the Prof-SC (Diversity Supplement)R01CA159868 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HOPPER, JOHN L, TERRY, MARY BETH · 2011 to 2015
$9.0MNRSA Training CoreTL1TR001875 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SPANN, MARISA N, TAYLOR, JACQUELYN Y · 2016 to 2025
$8.9MCANCER EPIDEMIOLOGY/BIOSTATISTICS/ENVIRONMENTAL SCIENCEST32CA009529 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NEUGUT, ALFRED I. · 1985 to 2012
$4.3MTraining Program in Cancer-related Population SciencesT32CA094061 · NCI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI NEUGUT, ALFRED I., TERRY, MARY BETH · 2017 to 2021
$1.1MNCATS NIH HHS TL1 TR001875NCI NIH HHS R01 CA159868NCI NIH HHS T32 CA009529NCI NIH HHS T32 CA094061NCI NIH HHS U01 CA164920
Abstract
Although physical activity is associated with lower breast cancer risk for average-risk women, it is not known if this association applies to women at high familial/genetic risk. We examined the association of recreational physical activity (self-reported by questionnaire) with breast cancer risk using the Prospective Family Study Cohort, which is enriched with women who have a breast cancer family history (
Indexed as
Breast NeoplasmsAdolescentAdultCohort StudiesExerciseFemaleHumansProspective StudiesRisk Factors
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Registered trials
NCT06405568ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.