Evidence map›Paper›PMID 31578157›Full record

ArticleInfectious diseases of poverty2019

Elimination of onchocerciasis in Africa by 2025: an ambitious target requires ambitious interventions.

Robert Colebunders, Wilma A Stolk, Joseph Nelson Siewe Fodjo, Charles D Mackenzie, Adrian Hopkins

Abstract read
In one paragraph

Article in Infectious diseases of poverty, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Onchocerciasis Elimination: Progress and Challenges.Research and reports in tropical medicine · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Robert ColebundersGlobal health Institute, University of Antwerp, Antwerp, Belgium. robert.colebunders@uantwerpen.be.ORCID http://orcid.org/0000-0002-1919-1340
Wilma A StolkDepartment of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Joseph Nelson Siewe FodjoGlobal health Institute, University of Antwerp, Antwerp, Belgium.
Charles D MackenzieTask force for Global Health, Decatur, Georgia, USA.
Adrian HopkinsNeglected and Disabling Diseases of Poverty Consultant, Gravesend, Kent, UK.

Funding

Bill&Melinda Gates Foundation, Neglected Tropical Diseaeses Modeling Consortium OPP1184344European Research Council 671055
6 · The paper itself

Abstract

To achieve the elimination of onchocerciasis transmission in all African countries will entail enormous challenges, as has been highlighted by the active discussion around onchocerciasis intervention strategies and evaluation procedures in this journal.Serological thresholds for onchocerciasis elimination, adapted for the African setting, need to be established. The Onchocerciasis Technical Advisory Subgroup of the World Health Organization is currently developing improved guidelines to allow country elimination committees to make evidence-based decisions. Importantly, onchocerciasis-related morbidity should not be forgotten when debating elimination prospects. A morbidity management and disease prevention (MMDP) strategy similar to that for lymphatic filariasis will need to be developed. This will require collaboration between the onchocerciasis elimination program, the community and other partners including primary health and mental health programs.In order to reach the goal of onchocerciasis elimination in most African countries by 2025, we should prioritize community participation and advocate for tailored interventions which are scientifically proven to be effective, but currently considered to be too expensive.

Indexed as

AfricaDisease EradicationHumansOnchocerciasisEliminationEpilepsyIvermectinMorbidityOnchocerciasisTarget

Identifiers

PMID31578157
PMCPMC6775645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.