Observational studyDementia and geriatric cognitive disorders2019
Cognitive Impairment Is Associated with Absolute Intraoperative Frontal α-Band Power but Not with Baseline α-Band Power: A Pilot Study.
Observational study in Dementia and geriatric cognitive disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- Anesthesia-induced electroencephalogram oscillations and perioperative outcomes in older adults undergoing cardiac surgery.Journal of clinical anesthesia · 2025Trial
- Effects of Remimazolam on Intraoperative Frontal Alpha Band Power Spectrum Density and Postoperative Cognitive Function in Older Adults Undergoing Lower Extremity Fractures Surgeries: A Randomized Controlled Trial.Clinical interventions in aging · 2024Trial
- Construction of a predictive model for postoperative subsyndromal delirium in patients undergoing brain tumor surgery.Acta neurologica Belgica · 2026Article
- Comparison of electroencephalogram waveforms in older patients with/without dementia after administration of midazolam: a prospective, observational comparative study.Journal of dental anesthesia and pain medicine · 2026Article
- Preoperative cognitive impairment predicts deep anaesthesia and higher postoperative pain in elderly patients: an observational study.BMC anesthesiology · 2025Observational
- Prediction of postoperative delirium in older adults from preoperative cognition and occipital alpha power from resting-state electroencephalogram.Age and ageing · 2025Observational
- Early alpha power in the frontal lobe area can predict delirium after cardiac surgery.Journal of cardiothoracic surgery · 2025Observational
- Intraoperative electroencephalogram features related to frailty in older patients: an exploratory prospective observational study.Journal of clinical monitoring and computing · 2024Observational
- Cognitive function mediates the relationship between age and anaesthesia-induced oscillatory-specific alpha power.Brain communications · 2024Article
- Differences in the EEG Power Spectrum and Cross-Frequency Coupling Patterns between Young and Elderly Patients during Sevoflurane Anesthesia.Brain sciences · 2023Article
- A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Ultrathin, Soft, Bioresorbable Organic Electrochemical Transistors for Transient Spatiotemporal Mapping of Brain Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Processed Electroencephalogram-Based Monitoring to Guide Sedation in Critically Ill Adult Patients: Recommendations from an International Expert Panel-Based Consensus.Neurocritical care · 2023Article
- Electroencephalogram Features of Perioperative Neurocognitive Disorders in Elderly Patients: A Narrative Review of the Clinical Literature.Brain sciences · 2022Review
- Machine-learning model predicting postoperative delirium in older patients using intraoperative frontal electroencephalographic signatures.Frontiers in aging neuroscience · 2022Article
- Unveiling age-independent spectral markers of propofol-induced loss of consciousness by decomposing the electroencephalographic spectrum into its periodic and aperiodic components.Frontiers in aging neuroscience · 2022Article
- Identification of individuals at risk for postoperative cognitive dysfunction (POCD).Therapeutic advances in neurological disorders · 2022Review
- Association Between Lower Preoperative Cognition With Intraoperative Electroencephalographic Features Consistent With Deep States of Anesthesia in Older Patients: An Observational Cohort Study.Anesthesia and analgesia · 2021Observational
- Electroencephalogram-Based Complexity Measures as Predictors of Post-operative Neurocognitive Dysfunction.Frontiers in systems neuroscience · 2021Article
- Propofol Requirement and EEG Alpha Band Power During General Anesthesia Provide Complementary Views on Preoperative Cognitive Decline.Frontiers in aging neuroscience · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
backgroundCognitive abilities decline with aging, leading to a higher risk for the development of postoperative delirium or postoperative neurocognitive disorders after general anesthesia. Since frontal α-band power is known to be highly correlated with cognitive function in general, we hypothesized that preoperative cognitive impairment is associated with lower baseline and intraoperative frontal α-band power in older adults.
methodsPatients aged ≥65 years undergoing elective surgery were included in this prospective observational study. Cognitive function was assessed on the day before surgery using six age-sensitive cognitive tests. Scores on those tests were entered into a principal component analysis to calculate a composite "g score" of global cognitive ability. Patient groups were dichotomized into a lower cognitive group (LC) reaching the lower 1/3 of "g scores" and a normal cognitive group (NC) consisting of the upper 2/3 of "g scores." Continuous pre- and intraoperative frontal electroencephalograms (EEGs) were recorded. EEG spectra were analyzed at baseline, before start of anesthesia medication, and during a stable intraoperative period. Significant differences in band power between the NC and LC groups were computed by using a frequency domain (δ 0.5-3 Hz, θ 4-7 Hz, α 8-12 Hz, β 13-30 Hz)-based bootstrapping algorithm.
resultsOf 38 included patients (mean age 72 years), 24 patients were in the NC group, and 14 patients had lower cognitive abilities (LC). Intraoperative α-band power was significantly reduced in the LC group compared to the NC group (NC -1.6 [-4.48/1.17] dB vs. LC -6.0 [-9.02/-2.64] dB), and intraoperative α-band power was positively correlated with "g score" (Spearman correlation: r = 0.381; p = 0.018). Baseline EEG power did not show any associations with "g."
conclusionsPreoperative cognitive impairment in older adults is associated with intraoperative absolute frontal α-band power, but not baseline α-band power.
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