Evidence map›Paper›PMID 31577943›Full record

ArticleCell reports2019

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning.

Matthew B Pomrenze, Simone M Giovanetti, Rajani Maiya, Adam G Gordon, Lauren J Kreeger, Robert O Messing

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 96 citations in OpenAlex.

  1. Review
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  7. Transcription factors Lef1 and Rest stimulate recovery from depressive states.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  8. Respiratory-Limbic Coupling via a Thalamic Circuit Alleviates Anxiety.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Article
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  14. Fear, anxiety, and the extended amygdala-bioRxiv : the preprint server for biology · 2025
    Article
  15. Article
  16. Article
  17. A Shared Threat-Anticipation Circuit Is Dynamically Engaged at Different Moments by Certain and Uncertain Threat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  18. Review
  19. Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Matthew B PomrenzeDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: pomrenze@stanford.edu.
Simone M GiovanettiDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA.
Rajani MaiyaDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA.
Adam G GordonDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA.
Lauren J KreegerDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA.
Robert O MessingDepartment of Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Department of Neurology, University of Texas at Austin, Austin, TX 78712, USA; Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: romessing@austin.utexas.edu.
The University of Texas at Austin · US

Funding

Neurochemical & Behavioral Correlates of ETOH EffectsT32AA007471 · NIAAA · UNIVERSITY OF TEXAS AUSTIN · PI Kimberly Nixon · 1987 to 2026
$9.2M
CRF neurons of the extended amygdala and alcohol drinkingR01AA026075 · NIAAA · UNIVERSITY OF TEXAS AT AUSTIN · PI MESSING, ROBERT O. · 2017 to 2021
$1.7M
NIAAA NIH HHS R01 AA026075NIAAA NIH HHS T32 AA007471
6 · The paper itself

Abstract

Central amygdala (CeA) neurons that produce corticotropin-releasing factor (CRF) regulate anxiety and fear learning. These CeA

Indexed as

AnimalsAnxietyCentral Amygdaloid NucleusCorticotropin-Releasing HormoneDynorphinsFeargamma-Aminobutyric AcidLearningMaleNeuronsNeuropeptidesNeurotensinRatsRats, WistarCorticotropin-Releasing HormoneDynorphinsgamma-Aminobutyric AcidNeuropeptidesNeurotensinamygdalaanxietycorticotropin releasing factordynorphinfeargamma-aminobutyric acidneurotensinRNA interference

Identifiers

PMID31577943
PMCPMC6879108
OpenAlexW2978286181

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.