Evidence map›Paper›PMID 31577511›Full record

ArticleAmerican journal of physiology. Cell physiology2020

Abnormal fertility, acrosome formation, IFT20 expression and localization in conditional

Zhenyu Wang, Yuqin Shi, Suheng Ma, Qian Huang, Yi Tian Yap, Lin Shi, Shiyang Zhang, Ting Zhou, Wei Li, Bo Hu and 5 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Cell physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. ELAPOR1 is a copper-dependent tethering factor driving proacrosomal vesicle fusion during acrosome biogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Intraflagellar Transport (IFT) and Sperm Formation.Advances in experimental medicine and biology · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Sperm Differentiation: The Role of Trafficking of Proteins.International journal of molecular sciences · 2020
    Review
  11. Mouse spermatogenesis-associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein.Developmental dynamics : an official publication of the American Association of Anatomists · 2020
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Zhenyu WangSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Yuqin ShiSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Suheng MaSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Qian HuangSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Yi Tian YapDepartment of Physiology, Wayne State University, Detroit, Michigan.
Lin ShiSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Shiyang ZhangSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Ting ZhouSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Wei LiDepartment of Physiology, Wayne State University, Detroit, Michigan.
Bo HuDepartment of Neurology, Wayne State University, Detroit, Michigan.
Ling ZhangSchool of Medicine, Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Wuhan University of Science and Technology, Wuhan, China.
Stephen A KrawetzDepartment of Obstetrics/Gynecology and Center for Molecular Medicine and Genetics, Wayne State University, Detroit, Michigan.
Gregory J PazourProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, Massachusetts.
Rex A HessDepartment of Comparative Biosciences, College of Veterinary Medicine, University of Illinois, Urbana, Illinois.
Zhibing ZhangDepartment of Physiology, Wayne State University, Detroit, Michigan.
Wayne State University · USWuhan University of Science and Technology · CNUniversity of Illinois Urbana-Champaign · USUniversity of Massachusetts Chan Medical School · US

Funding

Intraflagellar Transport Proteins in MiceR01GM060992 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Gregory J Pazour · 2001 to 2026
$10.3M
Dissection of the Structural Basis of MEIG1 in Assembling Sperm FlagellaR01HD076257 · NICHD · WAYNE STATE UNIVERSITY · PI ZHANG, ZHIBING · 2013 to 2017
$1.5M
The Role of Transcription Factor S-SOX5 in Male Fertility and Sperm Flagella FormationR03HD090306 · NICHD · WAYNE STATE UNIVERSITY · PI ZHANG, ZHIBING · 2017 to 2018
$145k
NICHD NIH HHS R01 HD076257NICHD NIH HHS R03 HD090306NIGMS NIH HHS R01 GM060992
6 · The paper itself

Abstract

GMAP210 (TRIP11) is a cis-Golgi network-associated protein and a Golgi membrane receptor for IFT20, an intraflagellar transport component essential for male fertility and spermiogenesis in mice. To investigate the role of GMAP210 in male fertility and spermatogenesis, floxed

Indexed as

Acrosome ReactionFertilityAcrosomeAnimalsCarrier ProteinsCytoskeletal ProteinsFemaleGene Knockout TechniquesGenetic Predisposition to DiseaseInfertility, MaleLitter SizeMaleMice, KnockoutMitochondriaPregnancySignal TransductionCarrier ProteinsCytoskeletal ProteinsIft20 protein, mouseTRIP11 protein, mouseacrosome formationGMAP210IFT20male fertilityTrip11

Identifiers

PMID31577511
PMCPMC6985835
OpenAlexW2977909398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.