Evidence map›Paper›PMID 31577436›Full record

ArticleJournal of natural products2020

Anibamine and Its Analogues: Potent Antiplasmodial Agents from

Yongle Du, Ana Lisa Valenciano, Yumin Dai, Yi Zheng, Feng Zhang, Yan Zhang, Jason Clement, Michael Goetz, David G I Kingston, Maria B Cassera

Open access · greenAbstract read
In one paragraph

Article in Journal of natural products, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Antimalarial Natural Products.Progress in the chemistry of organic natural products · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Yongle DuDepartment of Chemistry and Virginia Tech Center for Drug Discovery, M/C 0212, Virginia Tech, Blacksburg, Virginia 24061, United States.
Ana Lisa ValencianoDepartment of Biochemistry and Molecular Biology, and Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, Georgia 30602, United States.
Yumin DaiDepartment of Chemistry and Virginia Tech Center for Drug Discovery, M/C 0212, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID 0000-0002-9228-3671
Yi ZhengDepartment of Medicinal Chemistry, Virginia Commonwealth University, 800 E Leigh Street, Richmond, Virginia 23298, United States.
Feng ZhangDepartment of Medicinal Chemistry, Virginia Commonwealth University, 800 E Leigh Street, Richmond, Virginia 23298, United States.
Yan ZhangDepartment of Medicinal Chemistry, Virginia Commonwealth University, 800 E Leigh Street, Richmond, Virginia 23298, United States.ORCID 0000-0001-8934-7016
Jason ClementNatural Products Discovery Institute, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
Michael GoetzNatural Products Discovery Institute, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, Pennsylvania 18902, United States.
David G I KingstonDepartment of Chemistry and Virginia Tech Center for Drug Discovery, M/C 0212, Virginia Tech, Blacksburg, Virginia 24061, United States.ORCID 0000-0001-8944-246X
Maria B CasseraDepartment of Biochemistry and Molecular Biology, and Center for Tropical and Emerging Global Diseases (CTEGD), University of Georgia, Athens, Georgia 30602, United States.ORCID 0000-0001-6341-3169
Virginia Commonwealth University · USVirginia Tech · USDiscovery Institute · USUniversity of Georgia · US

Funding

Discovery and Mechanism of Antimalarial Natural ProductsR01AT008088 · NCCIH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASSERA, MARIA BELEN, CLEMENT, JASON ANDERSON · 2014 to 2018
$2.0M
NCCIH NIH HHS R01 AT008088
6 · The paper itself

Abstract

In our continuing search for novel natural products with antiplasmodial activity, an extract of

Indexed as

AlkaloidsAntimalarialsCell Line, TumorGuyanaHumansLauraceaeMolecular StructurePhytochemicalsPlasmodium falciparumPyridinesAlkaloidsanibamineAntimalarialsPhytochemicalsPyridines

Identifiers

PMID31577436
PMCPMC7103529
OpenAlexW2978008439

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.