ArticleeLife2019
Differential requirements for cyclase-associated protein (CAP) in actin-dependent processes of
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In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
6.5field-weighted citation impact, top 2% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 82 citations in OpenAlex.
- Clustering of host N-glycans by the microneme MIC1/4/6 complex licenses Toxoplasma rhoptry discharge.The EMBO journal · 2026Article
- Integrated Proteomic Screening Reveals Heme Enzyme Depletion Induces Cyst-like Vacuole Formation inInternational journal of molecular sciences · 2026Article
- Dual apical methyltransferases orchestrate motility initiation in apicomplexan parasites.Nature communications · 2026Article
- TgSEC14-LTP1 is a vacuole-secreted SEC14/CRAL-TRIO-like protein required for host DAG flux and PC homeostasis in T. gondii.Cell reports · 2026Article
- An apicoplast-localized GTPase is essential formSphere · 2026Article
- Tepsin and AP4 mediate transport from the trans-Golgi to the plant-like vacuole in toxoplasma.The Journal of cell biology · 2025Article
- Highly divergent apicomplexan cytoskeletons provide additional models for actin biology.The FEBS journal · 2025Review
- An apical ring protein essential for conoid complex assembly and daughter cell formation in Toxoplasma gondii.Nature communications · 2025Article
- Structural and functional characterization of TgGSK3, a druggable kinase in Toxoplasma gondii.Nature communications · 2025Article
- The critical role ofmBio · 2025Article
- GRA12 is a common virulence factor across Toxoplasma gondii strains and mouse subspecies.Nature communications · 2025Article
- Metabolic crosstalk between the mitochondrion and the nucleus is essential for Toxoplasma gondii infection.Communications biology · 2025Article
- A scaleable inducible knockout system for studying essential gene function in the malaria parasite.Nucleic acids research · 2025Article
- Apicomplexan mitoribosome from highly fragmented rRNAs to a functional machine.Nature communications · 2024Article
- Protocol for volume correlative light X-ray and electron microscopy of endothelial cells in mouse tissue.STAR protocols · 2024Article
- Optimization of a DiCre recombinase system with reduced leakage for conditional genome editing of Cryptosporidium.Parasites & vectors · 2024Article
- Toxoplasma gondii rhoptry discharge factor 3 is essential for invasion and microtubule-associated vesicle biogenesis.PLoS biology · 2024Article
- Metabolic plasticity, essentiality and therapeutic potential of ribose-5-phosphate synthesis in Toxoplasma gondii.Nature communications · 2024Article
- The α subunit of AMP-activated protein kinase is critical for the metabolic success and tachyzoite proliferation of Toxoplasma gondii.Microbial biotechnology · 2024Article
- Myosin F controls actin organization and dynamics inMolecular biology of the cell · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Alex HuntSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0001-7431-7156
Matthew Robert Geoffrey Russell *Electron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0003-4608-7669
Jeanette Wagener *Signalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0002-7227-4348
Robyn KentDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, United States.ORCID 0000-0002-2584-4694
Romain CarmeilleDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, United States.
Christopher J PeddieElectron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Lucy CollinsonElectron Microscopy Science Technology Platform, The Francis Crick Institute, London, United Kingdom.
Aoife HeaslipDepartment of Molecular and Cell Biology, University of Connecticut, Storrs, United States.
Gary E WardDepartment of Microbiology and Molecular Genetics, University of Vermont Larner College of Medicine, Burlington, United States.ORCID 0000-0003-4138-3055
Moritz TreeckSignalling in Apicomplexan Parasites Laboratory, The Francis Crick Institute, London, United Kingdom.ORCID 0000-0002-9727-6657
The Francis Crick Institute · GBUniversity of Connecticut · USUniversity of Vermont · US
Funding
Multiscale analysis of MyosinA-based motility in Toxoplasma gondiiR01AI139201 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARD, GARY E · 2019 to 2023
$2.8MMolecular mechanisms of dense granule trafficking in Toxoplasma gondiiR21AI121885 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HEASLIP, AOIFE · 2016 to 2017
$431kMapping the directionality of forces generated by T. gondii tachyzoites moving in 3DR21AI137767 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI WARD, GARY E · 2018 to 2019
$411kGENETIC ANALYSIS OF HUMAN LYMPHOID NEOPLASIAK04CA001189 · NCI · STANFORD UNIVERSITY · PI SKLAR, JEFFREY · 1987 to 1991
–Arthritis Research UK FC001189Arthritis Research UK FC001999NIAID NIH HHS R01 AI139201NIAID NIH HHS R21 AI121885NIAID NIH HHS R21 AI137767NIH HHS AI1218885NIH HHS AI137767NIH HHS AI139201Wellcome TrustWellcome Trust FC001189Wellcome Trust FC001999
Abstract
PubMed holds no abstract for this paper.
Indexed as
ActinsCell CommunicationCell DivisionGene DeletionProtein IsoformsProtozoan ProteinsToxoplasmaActinsProtein IsoformsProtozoan Proteinsactincell biologycyclase-associated proteininfectious diseasemicrobiologyparasitologyToxoplasma gondii
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.