Evidence map›Paper›PMID 31577170›Full record

ReviewPhysiology (Bethesda, Md.)2019

Ventilation/Perfusion Matching: Of Myths, Mice, and Men.

Alys R Clark, Kelly S Burrowes, Merryn H Tawhai

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. 3D Magnetic Resonance Spirometry.Scientific reports · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alys R ClarkAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.ORCID 0000-0001-5908-2862
Kelly S BurrowesAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.
Merryn H TawhaiAuckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.

Funding

Imaging Blood Flow, Ventilation, and Density InteractionsR01HL119201 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOPKINS, SUSAN R · 2016 to 2019
$2.5M
NHLBI NIH HHS R01 HL119201
6 · The paper itself

Abstract

Despite a huge range in lung size between species, there is little measured difference in the ability of the lung to provide a well-matched air flow (ventilation) to blood flow (perfusion) at the gas exchange tissue. Here, we consider the remarkable similarities in ventilation/perfusion matching between species through a biophysical lens and consider evidence that matching in large animals is dominated by gravity but in small animals by structure.

Indexed as

AnimalsGravitationHumansLungMicePhysiological PhenomenaRegional Blood FlowRespirationcomputational modelslungsperfusionventilation

Identifiers

PMID31577170
PMCPMC7002871

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.