Evidence map›Paper›PMID 31576801›Full record

Observational studyEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2019

New HIV-1 circulating recombinant form 94: from phylogenetic detection of a large transmission cluster to prevention in the age of geosocial-networking apps in France, 2013 to 2017.

Marc Wirden, Fabienne De Oliveira, Magali Bouvier-Alias, Sidonie Lambert-Niclot, Marie-Laure Chaix, Stéphanie Raymond, Ali Si-Mohammed, Chakib Alloui, Elisabeth André-Garnier, Pantxika Bellecave and 14 more

Open access · diamondAbstract readObservational Study
In one paragraph

Observational study in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 12 institutions in 1 country.

Marc WirdenSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique IPLESP, AP-HP, Hôpital Pitié Salpêtrière, Laboratoire de virologie, Paris, France.
Fabienne De OliveiraNormandie Université, UNIROUEN, EA2656 GRAM, CHU de Rouen, Laboratoire de virologie associé au CNR VIH, Rouen, France.
Magali Bouvier-AliasHU Henri Mondor, Laboratoire de virologie, Créteil, France.
Sidonie Lambert-NiclotAP-HP, Hopital Saint-Antoine, Laboratoire de virologie, Paris, France.
Marie-Laure ChaixAP-HP, Hôpital Saint-Louis, Laboratoire de virologie, INSERM U944, Paris, France.
Stéphanie RaymondLaboratoire de virologie, CHU Purpan de Toulouse, Toulouse, France.
Ali Si-MohammedLaboratoire de virologie CHU de Dijon, Dijon, France.
Chakib AllouiLaboratoire de virologie, Hôpital Avicenne, Bobigny, France.
Elisabeth André-GarnierLaboratoire de virologie, CHU Hôtel Dieu, Nantes, France.
Pantxika BellecaveLaboratoire de virologie CHU de Bordeaux, Bordeaux, France.
Brice MalveLaboratoire de virologie CHU de Nancy, Nancy, France.
Audrey MirandLaboratoire de virologie CHU de Clermont-Ferrand, Clermont-Ferrand, France.
Coralie PallierLaboratoire de virologie, Hôpital P. Brousse, Villejuif, France.
Jean-Dominique PovedaLaboratoire CERBA, Saint-Ouen-l'Aumône, France.
Theresa RabenjaLaboratoire du Grand Hôpital de l'Est Francilien, Jossigny, France.
Veronique SchneiderLaboratoire de virologie, Hôpital Tenon, Paris, France.
Anne Signori-SchmuckLaboratoire de virologie CHU de Grenoble, Grenoble, France.
Karl SteficLaboratoire de virologie CHU de Tours, Tours, France.
Vincent CalvezSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique IPLESP, AP-HP, Hôpital Pitié Salpêtrière, Laboratoire de virologie, Paris, France.
Diane DescampsLaboratoire de virologie, AP-HP, Hopital Bichat Claude Bernard, Univ Paris-Diderot, INSERM, IAME, CNR VIH, Paris, France.
Jean-Christophe PlantierNormandie Université, UNIROUEN, EA2656 GRAM, CHU de Rouen, Laboratoire de virologie associé au CNR VIH, Rouen, France.
Anne-Genevieve MarcelinSorbonne Université, INSERM, Institut Pierre Louis d'Epidémiologie et de Santé Publique IPLESP, AP-HP, Hôpital Pitié Salpêtrière, Laboratoire de virologie, Paris, France.
Benoit VisseauxLaboratoire de virologie, AP-HP, Hopital Bichat Claude Bernard, Univ Paris-Diderot, INSERM, IAME, CNR VIH, Paris, France.
French National Agency for Research on AIDS and Viral Hepatitis (ANRS) AC43 Study GroupMembers are listed in the acknowledgements.
Inserm · FRNormandie Université · FRSorbonne Université · FRUniversité Claude Bernard Lyon 1 · FRCentre Hospitalier Universitaire de Bordeaux · FRCentre Hospitalier Universitaire de Grenoble · FRCentre Hospitalier Universitaire de Tours · FRCHU Dijon Bourgogne · FRHôpital Avicenne · FRInstitut de Virologie · FRLaboratoire d'études sur les monothéismes · FRVirbac (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundEnding the HIV pandemic must involve new tools to rapidly identify and control local outbreaks and prevent the emergence of recombinant strains with epidemiological advantages.AimThis observational study aimed to investigate in France a cluster of HIV-1 cases related to a new circulating recombinant form (CRF). The confirmation this CRF's novelty as well as measures to control its spread are presented.MethodsPhylogenetic analyses of HIV sequences routinely generated for drug resistance genotyping before 2018 in French laboratories were employed to detect the transmission chain. The CRF involved was characterised by almost full-length viral sequencing for six cases. Cases' clinical data were reviewed. Where possible, epidemiological information was collected with a questionnaire.ResultsThe transmission cluster comprised 49 cases, mostly diagnosed in 2016-2017 (n = 37). All were infected with a new CRF, CRF94_cpx. The molecular proximity of this CRF to X4 strains and the high median viraemia, exceeding 5.0 log

Indexed as

PhylogenyRecombination, GeneticAdultCluster AnalysisDisease OutbreaksDNA, ViralDrug Resistance, ViralFranceHIV-1HIV InfectionsHumansMaleOnline Social NetworkingPhylogeographyReverse Transcriptase Polymerase Chain ReactionSequence AlignmentDNA, ViralHIV clusterHIV CRF94HIV OutbreakHIV Preventionphylogenetic analysis

Identifiers

PMID31576801
PMCPMC6774227
OpenAlexW2975211001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.