Evidence map›Paper›PMID 31576780›Full record

ArticleOphthalmic genetics2019

Modification of the

Winston Lee, Maarjaliis Paavo, Jana Zernant, Nicholas Stong, Zachary Laurente, Srilaxmi Bearelly, Takayuki Nagasaki, Stephen H Tsang, David B Goldstein, Rando Allikmets

Open access · greenAbstract readCase Reports
In one paragraph

Article in Ophthalmic genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Insights Into PROM1-Macular Disease Using Multimodal Imaging.Investigative ophthalmology & visual science · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Winston LeeDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Maarjaliis PaavoDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Jana ZernantDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Nicholas StongInstitute of Genomic Medicine, Columbia University , New York , New York , USA.
Zachary LaurenteBluhm Cardiovascular Institute, Northwestern Memorial Hospital, Northwestern University , Chicago , Illinois , USA.
Srilaxmi BearellyDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Takayuki NagasakiDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Stephen H TsangDepartment of Ophthalmology, Columbia University , New York , New York , USA.
David B GoldsteinInstitute of Genomic Medicine, Columbia University , New York , New York , USA.
Rando AllikmetsDepartment of Ophthalmology, Columbia University , New York , New York , USA.
Columbia University · USNorthwestern Memorial Hospital · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Precision medicine for ABCA4 disease: modifier allelesR01EY028203 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALLIKMETS, RANDO L · 2018 to 2021
$2.3M
Integrated clinical, genetic and functional analysis of the ABCA4 locusR01EY029315 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ALLIKMETS, RANDO L · 2019 to 2023
$2.2M
NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY028203NEI NIH HHS R01 EY029315
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAC133 AntigenAdolescentAdultAgedAged, 80 and overATP-Binding Cassette TransportersCase-Control StudiesFemaleFollow-Up StudiesHumansMacular DegenerationMaleMiddle AgedPedigreePhenotypeABCA4 protein, humanAC133 AntigenATP-Binding Cassette TransportersPROM1 protein, humanABCA4cone-rod dystrophyfamilymodifierPROM1

Identifiers

PMID31576780
PMCPMC6777736
OpenAlexW2971414040

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.